Infection, systemic inflammation, and Alzheimer's disease.

Microbes Infect

Department of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, 5200 North Lake Road, Merced, CA 95343, USA. Electronic address:

Published: August 2015

Alzheimer's disease (AD) is a leading cause of dementia among elderly. Yet, its etiology remains largely unclear. In this review, we summarize studies that associate systemic infection and neuroinflammation with AD, while highlighting that early-life or life-long exposure to infectious agents predisposes one to develop AD at a later age.

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Source
http://dx.doi.org/10.1016/j.micinf.2015.04.004DOI Listing

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