Effect of long-term pulsed electromagnetic field exposure on hepatic and immunologic functions of rats.

Wien Klin Wochenschr

Department of Surgery, Harbin Medical University, No. 23, You Zheng Street, Nan Gang District, 150001, Harbin, Heilongjiang Province, China.

Published: December 2015

AI Article Synopsis

  • The study investigated how long-term exposure to pulsed electromagnetic fields (PEMF) affects liver and immune functions in male rats.
  • Four groups of rats were used: a control group and three experimental groups exposed to different intensities of PEMF for 10 weeks.
  • Results showed that higher PEMF exposure increased liver enzyme levels and lipid peroxidation, while decreasing protective enzyme activity and immunoglobulin levels, indicating potential oxidative damage to the liver and spleen.

Article Abstract

Background: In this report, the effects of long-term pulsed electromagnetic field (PEMF) exposure on hepatic and immunologic functions were examined.

Methods: Male rats were randomly divided into four groups: a control group and three experimental groups exposed to a 50-Hz PEMF at 5, 10, or 20 mT for 10 weeks.

Results: Compared with the control group, activities of serum alanine aminotransferase and aspartate aminotransferase and concentrations of serum, liver, and spleen Metabolism of lipid peroxidation (MDA) in the 10- and 20-mT PEMF groups were significantly increased. The activities of Glutathione peroxidase (GSH-Px) and Superoxide Dismutase (SOD) in the serum, liver, and spleen and concentrations of serum immunoglobulins were significantly decreased.

Conclusion: These results demonstrate that long-term exposure to PEMF can lead to oxidative damage of the liver and spleen.

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Source
http://dx.doi.org/10.1007/s00508-015-0732-8DOI Listing

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