Objective: To analyze the epidemiological characteristics of malaria in Henan Province, and provide the basis for adjusting and formulating measures of malaria elimination timely.
Methods: The data of malaria cases during 2005 and 2013 in Henan Province was collected and analyzed using Microsoft Office Excel 2003 and SPSS14.0.
Results: Henan Province reported 17,803 malaria cases in 2005-2013, annual incidence was 0.2/100,000 to 5.2/100,000 with an average of 2.0/100,000. The cases were mainly distributed in Shangqiu (9079), Nanyang (4923), Xinyang (1449), Zhumadian (653), and Zhoukou (564), with more young male adults. The highest-risk population was farmers. More cases concentrated in August and September before 2010, but no obvious seasonal peak were seen after 2011. Vivax malaria occupied 95.4% (16,331/17,126) before 2010, but falciparum malaria was the major one after 2011. The laboratory confirmed cases during 2005-2013 took 54.6%. The median interval from symptom appearance to diagnosis was 4 d, and there was a significant difference among the years (χ2=437.2, P<0.01). The number of imported cases increased year by year, 26 cases in 2008 increased 146 cases in 2011. The reported malaria cases were imported cases during 2012 to 2013, of which 79.6% returned from the Africa, and 10.0% were from the Southeast Asia.
Conclusion: Malaria is still an important part of public health in Henan Province, and appropriate control measures and effective tools should be strengthened for eliminating the disease.
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BMC Genomics
January 2025
Henan Collaborative Innovation Center of Modern Biological Breeding, College of Agronomy, Henan Institute of Science and Technology, Xinxiang, 453003, China.
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Laboratory of Molecular Microbiology and Food Safety, Zhejiang University College of Animal Sciences, Hangzhou 310058, China; Hainan Institute of Zhejiang University, Sanya 572025, China; Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China. Electronic address:
Salmonella presents a significant threat to the health of animals and humans, especially with the rise of strains resistant to multiple drugs. This highlights the necessity for creating sustainable and efficient practical approaches to managing salmonellosis. The most recent and safest approach to combat antimicrobial resistance-associated infections is lytic bacteriophages.
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January 2025
School of Water Conservancy and Transportation, Zhengzhou University, Zhengzhou City, 450001, Henan Province, China. Electronic address:
Enhancing the understanding of the rainfall-runoff temporal dynamics in semi-arid and semi-humid regions is crucial for flood disaster mitigation. Loess Plateau is a unique environment within semi-arid and semi-humid regions, characterized by its deep loess soil, prevalent short-duration intense rainfall, and changes in underlying surface conditions. In this research, 25 catchments from the Loess Plateau were chosen to examine the temporal variations in event runoff responses across different time scales.
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January 2025
Department of Chemistry, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, New Cornerstone Science Foundation, Beijing, 100084, China. Electronic address:
Background: The widespread and evolution of RNA viruses, such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), highlights the importance of fast identification of virus subtypes, particularly in non-laboratory settings. Rapid and inexpensive at-home testing of viral nucleic acids with single-base resolution remains a challenge.
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Inflamm Res
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Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China.
Celastrol is one of the main active ingredients extracted from the plant Tripterygium wilfordii Hook F. A growing number of studies have shown that celastrol has various pharmacological effects, including anti-inflammation, anti-rheumatism, treatment of neurodegenerative diseases, and anti-tumor. This article systematically summarized the mechanism and role of celastrol in lipid metabolism and obesity, rheumatoid arthritis (RA), osteoarthritis (OA), gouty arthritis, inflammatory bowel disease, neurodegenerative diseases, and cancer and other diseases (such as diabetes, respiratory-related diseases, atherosclerosis, psoriasis, hearing loss, etc.
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