Ultrasound-Guided Fine Needle Aspiration (USFNA) of Thyroid Nodules; Does Aspiration Site Matter?

Iran J Radiol

Patonet Cytopathology Laboratory, Bursa, Turkey.

Published: April 2015

Background: The goal of ultrasound guided fine-needle aspiration (USFNA) is to obtain most cellular specimen that represents the nodule. However, there is substantial variability in specimen cellularity depending on the obtaining techniques. While performing USFNA, it is not clear whether the needle tip should be placed at hypovascular or hypervascular site of the nodule to obtain more cells for cytological analysis.

Objectives: The aim of the study was to assess whether USFNA of the hypovascular or hypervascular site of a thyroid nodule would reveal more cells for cytological analysis.

Patients And Methods: Twenty-three consecutive patients with solid thyroid nodules larger than 2 cm were aspirated under color Doppler sonography guidance. First pass was from the hypovascular site and the second pass from the hypervascular site. The aspirates were scored from 1-3 by cytologist according to number of cell groups.

Results: When only hypervascular site was used, adequate sampling was limited to 65% of the cases. When both sites were evaluated together, overall adequate sampling was 91%. Adding a sample from the hypervascular site to hypovascular aspirate increased the adequate sampling by 8%. The highest pathological score was achieved when both hypo- and hypervascular site aspirates were evaluated together.

Conclusions: The aspirates from the hypovascular and hypervascular sites of solid nodules are complementary and should be performed consecutively.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389176PMC
http://dx.doi.org/10.5812/iranjradiol.8307DOI Listing

Publication Analysis

Top Keywords

hypervascular site
24
hypovascular hypervascular
12
adequate sampling
12
aspiration usfna
8
thyroid nodules
8
site
8
cells cytological
8
site aspirates
8
hypervascular
7
hypovascular
5

Similar Publications

Background: The vertebral column is the most common site of bony metastasis. When indicated, surgical resection of hypervascular metastatic lesions may be complicated by significant blood loss, the need for blood transfusion, and incomplete tumor resection due to poor visualization and premature abortion of the operation. In select cases, preoperative arterial embolization of hypervascular metastatic tumors may help minimize intraoperative bleeding and reduce operative times.

View Article and Find Full Text PDF

Objective: To maximize local tumor control, stabilize affected bones, and preserve or replace joints with minimal interventional burden, thereby enhancing quality of life for empowered living.

Indications: Suitable for patients with bone metastases, particularly those with severe pain and/or fractures and appropriate life expectancy.

Contraindications: In primary bone tumors, refer to the sarcoma surgery team for evaluation of wide resection.

View Article and Find Full Text PDF

Hypovascular insulinoma with reduced microvessel density on histopathology: a case report.

Diabetol Int

October 2024

Department of Diabetes, Endocrinology and Metabolism and Department of Rheumatology and Clinical Immunology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194 Japan.

Article Synopsis
  • A 41-year-old man suspected of having insulinoma underwent various imaging tests, revealing a hypovascular tumor in the pancreas, which was ultimately diagnosed as a Grade 1 PanNET following surgery and pathology.
  • The tumor's low microvessel density (MVD) of 3.9% contributed to inconclusive imaging results, highlighting the need for thorough preoperative evaluations in cases of hypovascular PanNETs to ensure accurate diagnosis and treatment.
View Article and Find Full Text PDF

Prospective Longitudinal Analysis of Physiologic MRI-based Tumor Habitat Predicts Short-term Patient Outcomes in IDH-wildtype Glioblastoma.

Neuro Oncol

October 2024

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.

Background: This study validates MRI-based tumor habitats in predicting time-to-progression (TTP), overall survival (OS), and progression site in isocitrate dehydrogenase (IDH)-wildtype glioblastoma patients.

Methods: Seventy-nine patients were prospectively enrolled between January 2020 and June 2022. MRI, including diffusion-weighted and dynamic susceptibility contrast imaging, were obtained immediately post-operation and at three serial timepoints.

View Article and Find Full Text PDF

Prospective longitudinal analysis of imaging-based spatiotemporal tumor habitats in glioblastoma, IDH-wild type: implication in patient outcome using multiparametric physiologic MRI.

BMC Cancer

September 2024

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 43 Olympic-ro 88, Songpa-Gu, Seoul, 05505, Republic of Korea.

Article Synopsis
  • This study explores the use of MRI-based tumor habitat analysis to predict progression in glioblastoma patients after treatment with chemoradiotherapy.
  • Researchers will analyze MRI scans to categorize tumor regions into three types of habitats and track changes over time.
  • The goal is to link these habitat changes to patient outcomes, specifically time-to-progression and the site of tumor recurrence.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!