AI Article Synopsis
- Chronic cough is a major health issue, with current treatments showing varied effectiveness and a need for better options.
- Historical literature from East Asia reveals 331 natural products, such as plants, minerals, and animal substances, used to treat chronic cough over centuries.
- The study's top 10 most frequently used natural products show promise and suggest potential new avenues for developing effective cough therapies.
Article Abstract
Chronic cough is a significant health burden. Patients experience variable benefits from over the counter and prescribed products, but there is an unmet need to provide more effective treatments. Natural products have been used to treat cough and some plant compounds such as pseudoephedrine from ephedra and codeine from opium poppy have been developed into drugs. Text mining historical literature may offer new insight for future therapeutic development. We identified natural products used in the East Asian historical literature to treat chronic cough. Evaluation of the historical literature revealed 331 natural products used to treat chronic cough. Products included plants, minerals and animal substances. These natural products were found in 75 different books published between AD 363 and 1911. Of the 331 products, the 10 most frequently and continually used products were examined, taking into consideration findings from contemporary experimental studies. The natural products identified are promising and offer new directions in therapeutic development for treating chronic cough.
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| http://dx.doi.org/10.1177/1479972315583043 | DOI Listing |
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