Panax ginseng C. A. Meyer (P. ginseng) has been used as traditional medicine in Asian countries for more than 2,000 years. P. ginseng contains many active components such as ginsenosides, peptides, essential oil and polysaccharides, among which, P. ginseng polysaccharides were reported to have immunomodulating, anti-cancer, anti-adhesive and antioxidant activities. For better understanding of the structures and biological activities of all the ginseng polysaccharides, here the recent research achievements were reviewed. This review would be helpful for the relevant researchers to get useful information.
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Extraction of American ginseng polysaccharide by ultrasound-assisted deep eutectic solvents-based three-phase partitioning: Process optimization, structural characterization, and anti-ulcerative colitis study.
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December 2024
The Affiliated Dongguan Songshan Lake Central Hospital, Guangdong Provincial Key Laboratory of Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan 523808, China. Electronic address:
Three-phase partitioning (TPP) is promising for isolating bioactive polysaccharides, but t-butanol's environmental impact limits its application. Deep eutectic solvents can serve as a green and recyclable alternative to t-butanol. This study introduces an ultrasonic-assisted DES three-phase partitioning (UA-TPP-DES) system to extract and purify American ginseng polysaccharides (AGPs).
View Article and Find Full Text PDFMultiomics joint analysis reveals the potential mechanism of differences in the taproot thickening between cultivated ginseng and mountain-cultivated ginseng.
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Co-constructing Key Laboratory by Province and the Ministry of Science and Technology of Ecological Restoration and Ecosystem Management, College of Chinese Medicinal Material, Jilin Agricultural University, Changchun, 130118, China.
Panax ginseng is an important medicinal plant in China and is classified into two types: cultivated ginseng (CFCG) and mountain-cultivated ginseng (MCG). The two types of genetic varieties are the same, but the growth environments and management practices are different, resulting in substantial differences in their taproot morphology. Currently, there is a paucity of research on the internal mechanisms that regulate the phenotypic differences between cultivated ginseng and mountain-cultivated ginseng.
View Article and Find Full Text PDF[Comparative study on activation of latent HSV-1 induced "Shanghuo" by two different properties of traditional Chinese medicines].
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Guangdong Engineering Research Center for Disease Susceptibility and Traditional Chinese Medicine, Jinan University Guangzhou 510632, China Guangzhou Key Laboratory of Disease Susceptibility and Traditional Chinese Medicine Prevention and Treatment, Jinan University Guangzhou 510632, China Guangdong, Hong Kong and Macao Joint Laboratory of Universities, Guangdong Province, Jinan University Guangzhou 510632, China Institute of Traditional Chinese Medicine and Natural Medicines, Jinan University Guangzhou 510632, China.
Traditional Chinese medicine(TCM) theory suggests that "Shanghuo" is a comprehensive clinical symptom resulting from an imbalance of Yin and Yang. There is substantial clinical evidence showing that the consumption of warm or hot natured TCM can induce "Shanghuo". However, the pharmacological mechanisms and material basis of this phenomenon require further elucidation.
View Article and Find Full Text PDFComparative analysis of antioxidant activity and structural changes of polysaccharides between sulfur-fumigation and nonsulfur-fumigation.
Front Nutr
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School of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Introduction: (referred to Tianma in Chinese), the dried tuber of Bl. (Orchidaceae), is utilized as a medicine-food homology product. Sulfur fumigation is commonly employed in the processing of (GR).
View Article and Find Full Text PDFDissecting the anti-obesity components of ginseng: How ginseng polysaccharides and ginsenosides target gut microbiota to suppress high-fat diet-induced obesity.
J Adv Res
December 2024
Institute of Systems Medicine and Health Science, School of Chinese Medicine, Hong Kong Baptist University, 999077, Hong Kong; Research Centre for Standardization of Chinese Medicines, School of Chinese Medicine, Hong Kong Baptist University, 999077, Hong Kong; Department of Pharmaceutical Analysis and Metabolomics, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, China. Electronic address:
Introduction: Ginseng demonstrates therapeutic potential in treating obesity, with both experimental and clinical studies suggesting its anti-obesity effects are mediated by gut microbiota. Nonetheless, the specific chemical components responsible for this effect remain largely unidentified.
Objectives: This study aims to investigate the anti-obesity effects and mechanisms of ginseng polysaccharides (GP) and ginsenosides (GS), the primary chemical components of ginseng, with a focus on their impact on gut microbiota.
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