Objectives: The aim of this study was to find the best 3D reconstruction technique to visualize the endometrial-myometrial junction (EMJ).
Methods: Retrospective observational study on 240 stored 3D volumes of 80 patients. The first author reconstructed the 2D midcoronal image without volume contrast imaging (VCI), with VCI set at 4 mm and with VCI set at 2 mm. Three images per patient (240 images) were saved and integrated in the web-based electronic data capture software Clinical Data Miner (CDM) (http://cdm.esat.kuleuven.be). Five experienced gynaecologists analysed the images shown in random order. They scored the image quality (good, moderate, poor, insufficient) and described the EMJ of these images using IETA terminology (regular, irregular, interrupted, not defined). One of the examiners (CVP) also re-evaluated the same set of images after 12 days to assess intra-observer variability.
Results: The use of VCI significantly improved the recorded subjective image quality. The Fleiss' kappa coefficient for evaluating the inter-observer variability of the EMJ description using coronal view without VCI, with VCI at 4 mm and VCI at 2 mm were 0.36 ± 0.05, 0.34 ± 0.05 and 0.42 ± 0.05, respectively. The corresponding figures for the intra-observer variability were 0.58 ± 0.08, 0.36 ± 0.08 and 0.68 ± 0.07, respectively.
Discussion: In this study on 3D reconstructed coronal images of the uterine cavity, the 2 mm VCI slices gave the best quality images of the EMJ.
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J Biomed Opt
December 2024
Shanghai University of Medicine and Health Sciences, College of Medical Instruments, Shanghai, China.
Significance: The eye can be used as a potential monitoring window for screening, diagnosis, and monitoring of neurological diseases. Alzheimer's disease (AD) and vascular cognitive impairment (VCI) are common causes of cognitive impairment and may share many similarities in ocular signs. Multimodal ophthalmic imaging is a technology to quantify pupillary light reaction, retinal reflectance spectrum, and hemodynamics.
View Article and Find Full Text PDFJ Neurol Sci
December 2024
Department of Neurology, Zhongnan Hospital of Wuhan University, Wuhan, China. Electronic address:
Vascular cognitive impairment (VCI) stresses the vascular contributions to cognitive decline, ranging from mild to major forms. Except for symptomatic treatment for relevant vascular diseases, the other recommended strategy is to intervene in key vascular risk factors (VRFs) as early as possible. A considerable amount of previous research delineated the association of a specific factor with dementia, involving each risk factor discussed in the present review.
View Article and Find Full Text PDFJ Cardiovasc Dev Dis
December 2024
Cardiology Department, Mother and Child Health Institute of Serbia, 11070 Belgrade, Serbia.
Background: The vertical vein (VV) ligation during the total anomalous pulmonary venous return (TAPVR) correction is still controversial. Our study aimed to define the potential risk factors for VV persistence and their percutaneous occlusion.
Methods: The retrospective cohort study included 40 patients (26 males) with TAPVR treated at the tertiary referral center from 2005 to 2024.
J Cereb Blood Flow Metab
December 2024
Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Chronic cerebral hypoperfusion (CCH) is a crucial mechanism causing vascular cognitive impairment (VCI). Choline is metabolized by gut microbiota into trimethylamine N-oxide (TMAO), a risk factor of cardiovascular diseases and cognitive impairment. However, the impact of choline-TMAO pathway on CCH-induced VCI is elusive.
View Article and Find Full Text PDFEnviron Res
December 2024
School of Public Health, Anhui Medical University, Hefei, 230032, Anhui, China; Key Laboratory of Population Health Across Life Cycle (AHMU), MOE, Hefei 230032, China; NHC Key Laboratory of study on abnormal gametes and reproductive tract, Hefei 230032, China; Anhui Provincial Key Laboratory of Environment and Population Health Across the Life Course, Hefei, 230032, China. Electronic address:
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