AI Article Synopsis
- Tramadol is a synthetic opioid that also affects serotonin and norepinephrine levels, used to manage acute pain.
- Fibromyalgia is a chronic pain condition lacking FDA-approved treatments, with duloxetine, milnacipran, and pregabalin being the only effective medications.
- The paper reviews tramadol's effectiveness for fibromyalgia, finding reasonable evidence to support its use as a second-line option for tougher cases.
Article Abstract
Tramadol is a novel, synthetic opioid receptor agonist with serotonin-norepinephrine reuptake inhibitor properties that is often prescribed acutely for painful conditions. Fibromyalgia (FM) is a chronic painful condition that is difficult to treat and until more recently has had no approved medical treatments. Currently, the only US FDA-approved medications for FM include duloxetine, milnacipran and pregabalin. No opioid is approved for use in the treatment of FM. This paper specifically reviews the literature on tramadol use in FM and concludes that there is a fair evidence base to support its use as a second-line treatment for more resistant cases.
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Source |
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| http://dx.doi.org/10.1586/14737175.2015.1034693 | DOI Listing |
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