For the purpose of new detritylation agents search for microarray oligonucleotide synthesis we investigated applicability of [4-(4-methoxyphenyl)-2,6-dinitro-phenyl](phenyl)methyl 2,2,2-trichloroacetate for 4,4'-dimethoxytrityl group detritylation during oligonucleotide syntheses generating trichloroacetic acid at radiation by light with a length of wave of 405 nanometers. [4-(4-Methoxyphenyl)-2,6-dinitro-phenyl](phenyl)methyl 2,2,2-trichloroacetate has been successfully used for solid-phase oligonucleotide synthesis of desired oligonucleotides.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
oligonucleotide synthesis
8
[4-4-methoxyphenyl-26-dinitro-phenyl]phenylmethyl 222-trichloroacetate
8
[photogenerator trichloroacetic
4
trichloroacetic acid--a
4
acid--a perspective
4
perspective detritylation
4
detritylation agent
4
agent microchip
4
oligonucleotide
4
microchip oligonucleotide
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!