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Purpose Of The Study: Intraarticular fractures of the distal femur rank among the most severe musculoskeletal injuries. Various treatment options, such as plate osteosynthesis or retrograde nailing, can be employed. This study aims to evaluate the clinical outcomes and complications of intraarticular distal femoral fractures treated with retrograde femoral nail, with particular emphasis on C3 fractures.
View Article and Find Full Text PDFMesenchymal Stem Cell-Derived Extracellular Vesicles for Regenerative Applications and Radiotherapy.
Cell Transplant
January 2025
School of Basic Medicine Sciences, Shandong Second Medical University, Weifang, China.
Tissue repair is an extremely crucial part of clinical treatment. During the course of disease treatment, surgery, chemotherapy, and radiotherapy cause tissue damage. On the other hand, Normal tissue from accidental or therapeutic exposure to high-dose radiation can cause severe tissue damage.
View Article and Find Full Text PDFGold Nanoparticles and Chitosan as Innovative Compounds in Medicine and Cosmetology:A Review of Current Applications.
Curr Med Chem
January 2025
Faculty of Chemistry, University of Gdansk, Wita Stwosza, 6380308, Gdańsk, Poland.
The medical and cosmetic industries have developed in recent years, there has been a growing demand for new materials. Gold nanoparticles (Au NPs) and chitosan (CS) have been known and used for many years. Unfortunately, despite their numerous advantages and possible applications, such materials may possess certain disadvantages and limitations that constitute a problem in medical or cosmetic applications.
View Article and Find Full Text PDFComparison of the effect of early versus late surgical strategies on outcomes in patients with hand enchondromas complicated with pathological fractures.
Handchir Mikrochir Plast Chir
January 2025
Orthopaedics and Traumatology, University of Health Sciences Ankara Etlik City Hospital, Ankara, Turkey.
This study aimed to evaluate the advantages and disadvantages of early versus delayed single-stage surgery in patients with hand enchondromas who developed pathological fractures, focusing on local tumor control and hand function, to determine the optimal timing for surgery. Delayed surgical curettage may offer advantages regarding both local tumor control and hand function outcomes.Thirty-five patients who developed pathological fractures due to solitary hand enchondromas and underwent surgical treatment between 2015 and 2021 were analysed.
View Article and Find Full Text PDF[Isolated osseous tuberculosis : Differential diagnosis of treatment refractory osteomyelitis?].
Unfallchirurgie (Heidelb)
January 2025
Klinik für Orthopädie und Unfallchirurgie, BG Klinikum Duisburg, Großenbaumer Allee 250, 47249, Duisburg, Deutschland.
We report the case of a 66-year-old female patient with a treatment refractory disorder of wound healing of the knee, who had already been treated several times surgically and with antibiotics for several months. The examination revealed a skin defect with a fistula in the region of the knee joint. The X‑ray imaging showed an extensive bony defect of unclear etiology.
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