AI Article Synopsis
- The study investigates the impact of loss of dorsal acetabular rim (DAR) on the stability of cementless BFX acetabular cups in canines.
- The experimental tests, using both foam blocks and cadaveric pelvises, reveal that while normal loading shows no significant difference in stability with up to 50% DAR loss, failure occurred primarily due to bone fractures instead.
- Overall, it concludes that BFX cup stability seems unaffected by DAR loss within this threshold under standard physiological conditions.
Article Abstract
Background: Loss of dorsal acetabular rim (DAR) is a common sequela to canine hip dysplasia. The purpose of this study is to evaluate the effect of DAR loss on the initial stability of the cementless (BFX) acetabular cup. BFX cups were implanted into foam blocks reamed to resemble acetabulae with simulated 0, 25, 50, and 75% DAR loss. Models were tested in edge loading of the lateral surface of the cup with an indenter, and in centered loading with an articulated femoral prosthesis. Additionally, cups were implanted into paired cadaveric canine hemipelves with either no DAR depletion, or removal of 50% of the DAR, and acutely loaded to failure with an articulated femoral prosthesis.
Results: Mean load measured at 1 mm cup displacement during edge loading was not significantly different in foam blocks with loss of 0, 25, 50, and 75% DAR (360 ± 124 N, 352 ± 42 N, 330 ± 81 N, 288 ± 43 N, respectively; P = 0.425). Mean load to failure with centered loads was greatest in blocks with 0% DAR loss (2828 ± 208 N; P < 0.001), but was not significantly different between 25, 50, and 75% DAR loss (2270 ± 301 N, 1924 ± 157 N, 1745 ± 118 N). In cadaveric testing, neither mean load to failure (P = 0.067), stiffness (P = 0.707), nor energy (P = 0.228) were significantly different in control hemipelves and those with 50% depletion of the DAR. Failure in all acetabulae occurred due to acetabular bone fracture at forces in supraphysiologic ranges.
Conclusions: BFX cup stability under normal physiologic loads does not appear to be compromised in acetabulae with up to 50% DAR loss.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371846 | PMC |
| http://dx.doi.org/10.1186/s12917-015-0383-z | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A rare intersection: squamous cell carcinoma of the tonsil and the anti-TIF1 syndrome masquerade.
BMC Rheumatol
January 2025
Department of Rheumatology, Overton Brooks VA Medical Center, Shreveport, LA, USA.
Background: Dermatomyositis is a chronic inflammatory condition affecting muscles and skin, often associated with an increased risk of cancer. Specific autoantibodies, including anti-TIF1 (Transcription Intermediary Factor 1), have been linked to this risk. We present a case of dermatomyositis in a male patient positive for anti-TIF1 antibodies, subsequently diagnosed with squamous cell carcinoma of the tonsil, a novel association not previously documented.
View Article and Find Full Text PDFAdaptive ensemble loss and multi-scale attention in breast ultrasound segmentation with UMA-Net.
Med Biol Eng Comput
January 2025
Artificial Intelligence Lab, School of Computer and Information Sciences, University of Hyderabad, Hyderabad, 500046, India.
The generalization of deep learning (DL) models is critical for accurate lesion segmentation in breast ultrasound (BUS) images. Traditional DL models often struggle to generalize well due to the high frequency and scale variations inherent in BUS images. Moreover, conventional loss functions used in these models frequently result in imbalanced optimization, either prioritizing region overlap or boundary accuracy, which leads to suboptimal segmentation performance.
View Article and Find Full Text PDFIndividual and community level factors associated with household level food insecurity of Ethiopia: multilevel mixed effects analysis of 2021 Performance Monitoring for Action Ethiopia (PMA-ET).
BMC Nutr
January 2025
Lecturer of Biostatistics, Department of Public Health, College of Medicine and Health Science, Injibara University, Injibara, Ethiopia.
Background: People who face restricted or uncertain physical and economic access to safe, sufficient, and nutritious food to suit their dietary needs or food choices for a productive, healthy, and active life are said to be in a state or situation of food insecurity. There is a dearth of evidence of individual and community-level factors associated with household-level food insecurity in Ethiopia. Thus, this study aimed to assess individual and community-level factors associated with household-level food insecurity to fill the aforementioned gap.
View Article and Find Full Text PDFIdentifying the Factors That Drive Health Service Utilization Among Healthy and Non-Healthy Agers in a Sample of Older Ethiopians: A Cross-Sectional Study.
Health Sci Rep
January 2025
Department of Health Economics, Wellbeing, and Society National Centre for Epidemiology and Population Health, Australian National University Canberra Australian Capital Territory Australia.
Background And Aims: Population aging is associated with the rising incidence of chronic illness. This presents a significant challenge to healthcare systems, particularly in developing countries, as untreated chronic conditions can lead to years of disability and loss of independence straining health budgets and resources. Promoting healthy aging can be one avenue for mitigating these challenges.
View Article and Find Full Text PDFCollagen deposition in lung parenchyma driven by depletion of interstitial Lyve-1 macrophages prevents cigarette smoke-induced emphysema and loss of airway function.
Front Immunol
January 2025
Immunology Translational Research Programme, Yong Loo Lin School of Medicine, Department of Microbiology & Immunology, National University of Singapore, Singapore, Singapore.
Introduction: Collagen is essential for maintaining lung structure and function and its remodeling has been associated with respiratory diseases including chronic obstructive pulmonary disease (COPD). However, the cellular mechanisms driving collagen remodeling and the functional implications of this process in the pathophysiology of pulmonary diseases remain poorly understood.
Methods: To address this question, we employed ; mice with specific depletion of Lyve-1 macrophages and assessed the content, types and organization of collagen in lung compartments at steady state and after chronic exposure to cigarette smoke (CS).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!