Currently, there is no evidence whether ganciclovir, or its oral prodrug valganciclovir, penetrates into the cerebrospinal fluid of human infants treated for congenital cytomegalovirus infection. Here, we report a case study providing evidence that ganciclovir, administered as valganciclovir, reaches the infant's cerebrospinal fluid when used at the currently recommended dose for congenital cytomegalovirus infection.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389576PMC
http://dx.doi.org/10.1186/s13052-015-0132-8DOI Listing

Publication Analysis

Top Keywords

cerebrospinal fluid
12
congenital cytomegalovirus
12
cytomegalovirus infection
12
penetrates cerebrospinal
8
evidence ganciclovir
8
ganciclovir penetrates
4
fluid infant
4
infant congenital
4
infection currently
4
currently evidence
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!