Carbohydrate metabolism has been examined in 301 patients with chronic pyoderma over the course of combined therapy including sugar-reducing drugs; biochemical methods (measurement of the blood sugar on an empty stomach, Staub-Traugott double carbohydrate load test, measurement of the blood serum seromucoid) and radioimmunoassay of the blood serum immunoreactive insulin have been employed. Diabetes mellitus has been first diagnosed in 2.9% of patients, latent diabetes in 18.8%, and in 4.7% of the examinees the parameters indicate the risk of this condition development. Combined therapy improves the examined parameters, providing good immediate and late results. These data favor the use of sugar-reducing agents in multiple-modality therapy of patients with chronic pyoderma.
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