Colonic pseudolipomatosis.

Gastrointest Endosc

Gastroenterology Department, Centro Hospitalar de Lisboa Central, EPE.

Published: September 2015

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http://dx.doi.org/10.1016/j.gie.2015.03.1897DOI Listing

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Article Synopsis
  • - Pseudolipomatosis (PL) is a rare, benign condition linked to gas penetration in the colorectal mucosa, often occurring due to injury during endoscopic procedures, but its exact cause is still not fully understood.
  • - It's important for medical professionals to recognize PL to prevent unnecessary treatments, and techniques like immunohistochemistry can help distinguish it from similar conditions.
  • - A case study involving a 70-year-old man revealed duodenal pseudolipomatosis, marking a rare occurrence, as only two previous cases were reported, and no other instances were found in a review of over 500 duodenal biopsies.
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Article Synopsis
  • Colonic mucosal pseudolipomatosis is a rare, benign finding identified during endoscopies, characterized by white-yellow plaques on the colon.
  • Eight patients exhibited a unique form of colitis linked to technical issues with the disinfection process of the endoscope used during colonoscopy.
  • After addressing the malfunction, no further cases were reported, emphasizing the need for strict verification of disinfection procedures to prevent endoscopically induced lesions.
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Pseudolipomatosis of the Colon.

Clin Gastroenterol Hepatol

August 2024

Department of Basic Science Education, Virginia Tech Carilion School of Medicine, Roanoke, Virginia; Department of Pathology, Dominion Pathology Associates, Roanoke, Virginia.

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BACKGROUND Colonic pseudolipomatosis (CP) can pose a diagnostic challenge due to its rare incidence and multiple presentations, most of them not very familiar to the endoscopist. Its etiology and pathogenesis have not been completely clarified. It can be related to mucosal iatrogenic injury caused during endoscopic examination or to chemical injury caused by residual disinfectants on the surface of the scope after cleansing.

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