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Evaluation of Inflammatory Activity of Extraocular Muscles in Thyroid Associated Orbitopathy by [Ga]DOTATATE PET/CT.
Mol Imaging Biol
January 2025
Department of Nuclear Medicine (PET Center), Key Laboratory of Biological Nanotechnology of National Health Commission, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410000, China.
Purpose: The accurate assessment of inflammatory activity of the extraocular muscles (EOMs) in thyroid associated ophthalmopathy (TAO) is crucial for formulating subsequent treatment strategies and prognostic judgments. This study aims to explore the efficacy of using [Ga]DOTATATE PET/CT to assess the inflammatory activity of EOMs in TAO patients.
Procedures: This study enrolled 22 TAO patients and 6 healthy volunteers, all of whom underwent orbital [Ga]DOTATATE PET/CT.
TOM500: A Multi-Organ Annotated Orbital MRI Dataset for Thyroid Eye Disease.
Sci Data
January 2025
Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
This study presents TOM500, a comprehensive multi-organ annotated orbital magnetic resonance imaging (MRI) dataset. It includes clinical data, T2-weighted MRI scans, and corresponding segmentations from 500 patients with thyroid eye disease (TED) during their initial visit. TED is a common autoimmune disorder with distinct orbital MRI features.
View Article and Find Full Text PDFTopological features of brain functional networks are reorganized during chronic tinnitus: A graph-theoretical study.
Eur J Neurosci
January 2025
Department of Ear, Nose, and Throat, The First Affiliated of Soochow University, Suzhou, China.
This study aimed to investigate the topological properties of brain functional networks in patients with tinnitus of varying durations. A total of 51 tinnitus patients (divided into recent-onset tinnitus (ROT) and persistent tinnitus (PT) groups) and 27 healthy controls (HC) were recruited. All participants underwent resting-state functional MRI and audiological assessments.
View Article and Find Full Text PDFCongenital conjunctival cyst detected by prenatal ultrasound.
Am J Ophthalmol Case Rep
March 2025
University of South Carolina/Prisma Health, Columbia, SC, USA.
Purpose: The purpose of this manuscript is to report a rare case of an orbital cyst detected intrauterine with sonography.
Observation: A 23-year-old female presented for routine prenatal monitoring when an orbital cyst was detected with a transabdominal ultrasound. Uncomplicated cesarean section was performed at 38 weeks gestation with proptosis of the left globe being noted on ophthalmic examination of the newborn.
Unravelling the Unseen: A Case Series Exploring the Enigmas of Traumatic Optic Neuropathy.
Cureus
December 2024
Department of Ophthalmology, Sir Takhtasinhji General Hospital, Bhavnagar, IND.
Traumatic optic neuropathy (TON) is a rare condition resulting from damage to the optic nerve due to craniofacial trauma. It can present as direct or indirect injuries, with mechanisms ranging from mechanical disruption by fractures in direct TON to transmitted forces causing shearing and ischemia in indirect TON. These injuries often lead to significant visual impairment or complete vision loss, requiring timely diagnosis and intervention.
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