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Perioperative anaphylaxis manifesting as cardiac arrest during cardiac surgery.
Allergy Asthma Proc
January 2025
Perioperative anaphylaxis is a serious entity with high morbidity and mortality. Perioperative anaphylaxis can be caused by any of the multitude of medications and substances used in anesthesia and surgery, and the most common causes include neuromuscular blocking agents, antibiotics, antiseptics, latex, and dyes. The differential diagnosis of perioperative anaphylaxis is wide from both an immunologic and a nonimmunologic standpoint.
View Article and Find Full Text PDFExploring the Landscape of Perioperative Immediate Hypersensitivity: A Comprehensive 6-Year Monocentric Observational Analysis on Epidemiology and Risk Factors.
Int Arch Allergy Immunol
November 2024
Anaesthesiology and Critical Care Medicine Department, Croix-Rousse University Hospital, Hospices Civils de Lyon, Lyon, France.
Introduction: Perioperative immediate hypersensitivity (POH) is a rare complication estimated at 1/10,000 anaesthesia. The objective of our study was to investigate the risk factors of POH over a 6-year period in a French teaching hospital.
Materials And Methods: A single-centre retrospective descriptive epidemiological study of patients treated in the operating room from January 2016 to December 2021 with and without POH.
Anaphylactic shock during SpaceOAR Vue hydrogel procedure.
Urol Case Rep
November 2024
Department of Urology, Detroit Medical Center, 4160 John R St., Harper Professional Building, Suite 1021, Detroit, MI, 48201, United States.
In this report, we present a unique and rare case of an intraoperative anaphylactic shock leading to cardiac arrest during the SpaceOAR Vue™ hydrogel procedure in a 70-year-old patient undergoing External Beam Radiation Therapy (EBRT) for advanced localized prostate cancer. To our knowledge, this is the first urologic case report documenting this adverse reaction associated with the placement of the SpaceOAR Vue product. We discuss the possible culprits, including the hydrogel's polyethylene glycol (PEG) and iodine content, perioperative antibiotics, and local lidocaine anesthetic, and propose relevant considerations for clinicians administering rectal hydrogel spacers.
View Article and Find Full Text PDFTiming of onset of intraoperative transfusion anaphylaxis: a literature review.
Nagoya J Med Sci
August 2024
Department of Anesthesiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Clinical diagnosis of intraoperative transfusion anaphylaxis using clinical symptoms is challenging and should be made carefully, as an incorrect clinical diagnosis can exacerbate surgical bleeding secondary to stopping a clinically indicated blood transfusion. The timing of onset of anaphylaxis to start of transfusion may be the key to correctly diagnosing intraoperative transfusion anaphylaxis clinically. However, the reliability of this measure remains unknown.
View Article and Find Full Text PDFAssessment of Perioperative Protamine Reactions in Patients With Fish Allergies: A Retrospective Observational Study.
J Cardiothorac Vasc Anesth
December 2024
Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Phoenix, AZ. Electronic address:
Objectives: To retrospectively assess the incidence and severity of perioperative protamine reactions in adult patients with documented history of fish allergy.
Design: Retrospective observational study.
Setting: Large academic tertiary referral center.
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