AI Article Synopsis
- A clinical study compared the effectiveness and safety of ropivacaine versus bupivacaine for spinal anesthesia in lower abdominal and limb surgeries.
- The study involved 70 patients, with 35 receiving bupivacaine and 35 receiving ropivacaine, and measured factors like onset time and duration of sensory and motor blockade.
- Results showed that ropivacaine led to faster onset of sensory blockade, shorter duration of motor blockade, and no side effects, making it a safe alternative to bupivacaine for quicker recovery and ambulation.
Article Abstract
Background: A prospective randomized clinical study was conducted to study the efficacy and safety of ropivacaine with bupivacaine intrathecally for lower abdominal and lower limb surgeries.
Material And Methods: 70 patients aged between 18 to 65 years were randomized into two groups, n = 35 in each group. Group A received 3 ml of (0.5%) isobaric bupivacaine (15 mg) and Group B 3 ml of (0.75%) isobaric ropivacaine (22.5 mg). Spinal anesthesia procedure was standardized. Haemodynamic parameters, onset and duration of sensory and motor blockade, level achieved, regression and side effects were compared between the two groups.
Results: Onset and regression of sensory blockade in ropivacaine group was faster with a P < 0.001 which was statistically significant. Onset of motor blockade was rapid in both the groups but duration of motor blockade was significantly shorter in ropivacaine group. Excellent analgesia, with no side effects and stable haemodynamics was noted in ropivacaine group.
Conclusion: Hence ropivacaine was safe and equally effective as bupivacaine for lower abdominal and lower limb surgeries with early motor recovery, providing early ambulation.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173549 | PMC |
| http://dx.doi.org/10.4103/0259-1162.123252 | DOI Listing |
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