Comparative Genomics of the Mucoid and Nonmucoid Strains of Streptococcus pyogenes, Isolated from the Same Patient with Streptococcal Meningitis.

Genome Announc

Department of Infection Control and Immunology and Graduate School of Infection Control Sciences, Kitasato Institute for Life Sciences, Kitasato University, Minato-ku, Tokyo, Japan

Published: April 2015

Mucoid (MTB313) and nonmucoid (MTB314) strains of group A streptococcus emm type 1 were simultaneously isolated from a single patient suffering from streptococcal meningitis. Whole-genome sequencing revealed that MTB313 carried a nucleotide substitution within rocA, which generated an amber termination codon.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400423PMC
http://dx.doi.org/10.1128/genomeA.00221-15DOI Listing

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