AI Article Synopsis
- The study examined how age and sex influence the diagnosis of thin malignant melanoma (MM), involving 2,430 patients.
- It found that thinner cases (in situ-T1) were more common than thicker ones (T2-T4), with Breslow thickness increasing with age.
- Results showed women had significantly thinner melanoma compared to men, and overall, age and sex accounted for only a small portion (3.64%) of the differences in early detection rates for MM.
Article Abstract
Age and sex have been identified as predictors of outcome in malignant melanoma (MM). This aim of this multicentre, cross-sectional study was to analyse the role of age and sex as explanatory variables for the diagnosis of thin MM. A total of 2430 patients with MM were recruited. Cases of in situ-T1 MM were more frequent than T2-T4 MM (56.26% vs. 43.74%). Breslow thickness increased throughout decades of life (analysis of variance (ANOVA) p < 0.001), with a weak correlation between Breslow thickness and patient's age (r = 0.202, p < 0.001). Breslow thickness was significantly less in women (1.79 vs. 2.38 mm, p = 0.0001). Binary logistic regression showed a significant (p < 0.001) odds ratio for age 0-29 years (1.18), and 30-59 years (1.16), and for women (1.09). Age and sex explained 3.64% of the variation observed in Tis-T1 frequency (R2 = 0.0364). Age and sex appear to explain a low percentage of the variation in the early detection of MM.
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| http://dx.doi.org/10.2340/00015555-2115 | DOI Listing |
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