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Antimicrobial resistance, virulence gene profiling, and genetic diversity of multidrug-resistant Pseudomonas aeruginosa isolates in Mazandaran, Iran.
BMC Microbiol
December 2024
Department of Microbiology and Virology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Background: Pseudomonas aeruginosa is a major cause of healthcare-associated infections (HAIs), particularly in immunocompromised patients, leading to high morbidity and mortality rates. This study aimed to investigate the antimicrobial resistance patterns, virulence gene profiles, and genetic diversity among P. aeruginosa isolates from hospitalized patients in Mazandaran, Iran.
View Article and Find Full Text PDFChanging the culture: increasing captured intraoperative anaesthesia-related safety events through targeted interventions.
BMJ Open Qual
December 2024
Anesthesiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Background: There is an under-reporting of anaesthesia-related safety events. Incident-capturing systems (ICSs) are essential for patient safety monitoring, identifying risks and ongoing opportunities for improvement. After a literature review and assessment of our current ICSs, we concluded that our institution lacked a reliable anaesthesia-specific ICS system, leading to under-reporting of anaesthesia-related safety events.
View Article and Find Full Text PDFMolecular biomarkers associated with TBI outcome in individuals of Black racial identity or African ancestry: a narrative review.
World Neurosurg
December 2024
College of Medicine, SUNY Downstate Health Sciences University, Brooklyn, New York, USA; Global Neurosurgery Laboratory, SUNY Downstate Health Sciences University, Brooklyn, New York, USA; Department of Neurology, One Brooklyn Health/Brookdale University Hospital and Medical Center, Brooklyn, New York, USA; Department of Neurology; SUNY Downstate Health Sciences University, Brooklyn, New York, USA; Institute for Genomics in Health, SUNY Downstate Health Sciences University, Brooklyn, New York, USA; Division of Neurosurgery, Department of Surgery, SUNY Downstate Health Sciences University, Brooklyn, New York, USA; Department of Community Health Sciences, School of Public Health, SUNY Downstate Health Sciences University; Department of Surgery, One Brooklyn Health/Brookdale University Hospital and Medical Center, Brooklyn, New York, USA. Electronic address:
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide and a major global health concern. In the United States (US), individuals of Black or African American racial identity experience disproportionately higher rates of TBI and suffer from worse post-injury outcomes. Contemporary research agendas have largely overlooked or excluded Black populations, resulting in the continued marginalization of Black patient populations in TBI studies, thereby limiting the generalizability of ongoing research to patients in the US and around the world.
View Article and Find Full Text PDFFatal dengue virus infection in an unvaccinated traveler.
Eur J Clin Microbiol Infect Dis
December 2024
Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Dengue is an increasing threat to individuals living in or visiting endemic countries. Effective vaccines have become available, but their use in travelers is typically only recommended to individuals with documented prior infection. We present a fatal case of severe dengue in an unvaccinated traveler without known prior dengue virus infection but longitudinal serologic and molecular evidence for secondary infection.
View Article and Find Full Text PDFGlobal, regional, and national burdens of intracerebral hemorrhage and its risk factors from 1990 to 2021.
Eur J Neurol
January 2025
Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Background And Purpose: The aim of this study was to assess the intracerebral hemorrhage (ICH) burden in 204 countries and territories worldwide from 1990 to 2021, disaggregated by sex, age, and sociodemographic index (SDI) at the global, regional, and country levels.
Methods: Data from the 2021 Global Burden of Disease Study (GBD) were used to calculate age-standardized prevalence (ASPR), incidence (ASIR), death (ASDR), and disability-adjusted life year (DALY) rates for ICH. The estimated annual percentage change (EAPC) was used to assess time patterns.
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