Experience gained with the use of plasmapheresis in 336 children with different diseases is described. In patients with bacterial and inflammatory processes, the effect was attained after the first plasmapheresis session. Acuity of the immunomediated processes decreased after exfusion of 2-3.5 volumes of the circulating plasma. The replacement of the exfused plasma by protein blood preparations was made only in patients with hepatodystrophy, bacterial and inflammatory diseases, and immune complex diseases combined with the signs of consumption coagulopathy. After a course of plasmapheresis there was a significant lowering of total protein, albumin and immunoglobulin G. The reduction of the content of hemoglobin and red blood cells was related to hemodilution Iron homeostasis remained unchanged. The use of plasmapheresis in atopic dermatitis without preventive administration of an antibiotic is associated with the risk of the development of post-catheterization thrombophlebitis.
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