Ependymomas are glial tumors derived from ependymal cells lining the ventricles and the central canal of the spinal cord. Two thirds of ependymomas arise in the infratentorial or intraventricles, whereas one-third are located in supratentorial space. But supratentorial "cortical" ependymomas are very rare. We report a case of a cortical ependymoma in a 17-year-old boy. The patient presented with transient recurrent right weakness and diplopia. This tumor was located in the left parieto-occipital region and he had gross total excision. Microscopy and immunohistochemistry showed grade III differentiation ependymoma.
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http://dx.doi.org/10.4103/2277-9175.153896 | DOI Listing |
Radiol Case Rep
January 2025
Radiology Department, Faculty of Medicine and Pharmacy, Specialities hospital, Mohammed V University, Rabat, Morocco.
Dysembryoplastic neuroepithelial tumors (DNETs) are benign cortical tumors frequently associated with medically incurable focal epilepsy. These tumors occur most commonly in children. Given the fact that they rarely become malignant, the long-term prognosis in terms of mortality is excellent, however its similar appearance with other tumors of the central nervous system increases the potential for misdiagnosis and the risk of a pejorative clinical evolution.
View Article and Find Full Text PDFInt J Surg Case Rep
October 2024
Department of Neurosurgery, Aleppo University Hospital, University of Aleppo, Aleppo, Syrian Arab Republic.
Introduction And Importance: Ependymomas arise from the ependymal cells that line the brain ventricles, and central canal. In children most of them are benign. However, cortical anaplastic ependymomas are very rare in pediatrics.
View Article and Find Full Text PDFEur J Surg Oncol
December 2024
Department of Neurosurgery, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China. Electronic address:
PLoS One
July 2024
Cancer Signaling and Microenvironment Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America.
AJNR Am J Neuroradiol
November 2024
From the Department of Radiology, Mayo Clinic (N.S., G.B., A.D., V.G., A.A.), Jacksonville, Florida.
The 2021 World Health Organization Classification of Tumors of the Central Nervous System (CNS5), introduced significant changes, impacting tumors ranging from glial to ependymal neoplasms. Ependymal tumors were previously classified and graded based on histopathology, which had limited clinical and prognostic utility. The updated CNS5 classification now divides ependymomas into 10 subgroups based on anatomic location (supratentorial, posterior fossa, and spinal compartment) and genomic markers.
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