Deepened pockets are a challenge because they offer an anaerobic niche and because of their inaccessibility to personal plaque control measures. Scaling and root planing followed by regular professional plaque removal are effective in arresting the progress of most chronic adult periodontitis. Only when pockets remain inflamed after repeated thorough professional treatment during several months can a surgical pocket elimination technique be used. The results will depend on the type of attachment loss (horizontal vs. irregular) the root anatomy (furcations) and the training level of the operator, general practitioner or periodontologist. There is an increasing trend in the anterior parts of the oral cavity (monoradicular teeth easily accessible for plaque control) to use the Widman technique. Long-term data concerning the stability of this new attachment are lacking. Gingivectomy is less elaborate, does not imply a high-level sterile environment like for mucoperiosteal flap surgery, but leads to phonetic and esthetic side-effects when used in frontal areas. In the distal areas the apically displaced and the shortened repositioned flap techniques are effective in a long-term perspective if regular postoperative monitoring is respected. Discussion remains concerning the stability of a new connective tissue attachment vs. a long epithelial attachment. A recent breakthrough is the so-called Guided Tissue Regeneration where by means of a submucosally membrane the periodontal ligament cells are allowed to regenerate the different periodontal tissue compartments. Preliminary results are very encouraging but need further evaluation.
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J Oral Biol Craniofac Res
January 2025
Department of Periodontics, Vivekanandha Dental College for Women, India.
Background And Objective: Periodontitis and dental caries are among the most prevalent oral diseases, with chronic periodontitis being a multifactorial, infectious condition that leads to inflammation in the supporting structures of the teeth, progressive attachment loss, and bone resorption. Chronic periodontitis is driven by a consortium of pathogenic microorganisms. This study aimed to evaluate the efficacy of virgin coconut oil (VCO) pulling in reducing the microbial load and inflammatory mediators responsible for chronic periodontitis, in comparison to chlorhexidine (CHX) mouthwash and distilled water.
View Article and Find Full Text PDFCoron Artery Dis
January 2025
Intensive Cardiac Care Department, Ziv Medical Center.
Background: Coronary artery calcium, a marker of coronary atherosclerosis, is often identified on noncoronary chest computed tomography (CT). We wanted to evaluate the correlation between the presence of coronary plaques in coronary artery catheterization and coronary calcifications as shown in noncardiac chest CT.
Methods: A retrospective case-control study consisting of cases (N = 63) and controls (N = 29), aged 18-70 years old, residing in northern Israel and treated in the Intensive Cardiac Care Unit of Ziv Medical Center, between January 2020 and November 2022.
BMC Oral Health
January 2025
Dentistry and Maxillo-Facial Surgery Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of Verona, Piazzale L.A. Scuro 10, 37134, Verona, Italy.
Introduction: Orofacial cleft impacts jawbone and dental development and function, often with consequences for oral health. The first in this two-part systematic review of the literature on oral health in persons with cleft lip and/or palate focuses on periodontal parameters and composition of oral bacterial flora, while the second analyzes data on dental caries.
Materials And Methods: Four databases (PubMed, Cochrane, Scopus, Web of Science) were searched for studies that compared periodontal parameters, caries index, and microbiota composition between persons with cleft lip and/or palate and healthy controls.
Sci Rep
January 2025
Ministry of Health, Ankara Ottoman Oral and Dental Health Center, Ankara, Turkey.
Chlorhexidine (CHX) is the most commonly used mouthwash with proven antiplaque and antibacterial activity. The aim is to evaluate the effect of vitamin C (VitC) in CHX mouthwash on plaque accumulation and gingivitis, and to compare it with CHX alone mouthwash and antiseptic phenol-containing mouthwashes. This study conducted as a multicenter, randomized, controlled, double-blind, parallel design clinical study.
View Article and Find Full Text PDFBiochem Genet
January 2025
Department of Physiology, University of Louisville School of Medicine, Louisville, KY, 40202, USA.
Although DNA methyltransferase 1 (DNMT1) and RNA editor ADAR triplications exist in Down syndrome (DS), their specific roles remain unclear. DNMT methylates DNA, yielding S-adenosine homocysteine (SAH), subsequently converted to homocysteine (Hcy) and adenosine by S-adenosine homocysteine (Hcy) hydrolase (SAHH). ADAR converts adenosine to inosine and uric acid.
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