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12-month neurological and psychiatric outcomes of semaglutide use for type 2 diabetes: a propensity-score matched cohort study.
EClinicalMedicine
August 2024
Department of Psychiatry, University of Oxford, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, United Kingdom.
Background: While semaglutide, approved for type-2 diabetes mellitus (T2DM), is being investigated as a treatment for brain disorders, concerns over adverse neuropsychiatric events have emerged. More data are therefore needed to assess the effects of semaglutide on brain health. This study provides robust estimates of the risk of neurological and psychiatric outcomes following semaglutide use compared to three other antidiabetic medications.
View Article and Find Full Text PDF"I am sick, but that's not all that I am": patient perspectives on psychological adaptation over time to inborn errors of immunity.
J Community Genet
January 2025
Centralized Sequencing Program, National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, MD, USA.
Inborn errors of immunity (IEI) are rare heritable disorders of the immune system predisposing to atypical infections, autoimmunity, inflammation, and risk of malignancy. Adaptation is the process of incorporating stressful experiences into one's life; these experiences may include onset of illness, receiving a diagnosis, or suffering without a diagnosis. Poor adaptation is linked to adverse outcomes including psychiatric comorbidities and decreased well-being.
View Article and Find Full Text PDFImmigrant Background and Rape Conviction: A 21-Year Follow-Up Study in Sweden.
J Interpers Violence
January 2025
Center for Primary Health Care Research, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
While extensive research exists on the severe consequences among rape victims, little is known about specific predictors in relation to rape convictions among immigrants to Europe. This study from Sweden (having one of Europe's highest per capita rates of rape) investigates individuals convicted of rape, aggravated rape, attempted rape, or attempted aggravated rape, collectively termed as rape+, against women 18 years or older, from 2000 to 2020. In this case-control study, we analyzed data from Swedish population-based registers.
View Article and Find Full Text PDFComparison of Ceramic Bonding to Cobalt-Chromium, Zirconia and Nickel-Chromium Alloys Fabricated Using of Various Techniques.
J Biomed Mater Res B Appl Biomater
January 2025
Dental Materials Unit, Center for Dental Medicine, Clinic for Masticatory Disorders and Dental Biomaterials, University of Zurich, Zurich, Switzerland.
The purpose of this study was to evaluate the characteristics of the ceramic bonding to cobalt-chromium (Co-Cr) alloys fabricated by casting, milling, and additive manufacturing, compared with zirconia and nickel-chromium. One hundred specimens (N = 100), prepared with the dimensions of 25 × 3 × 0.5 mm, were assigned to five groups (n = 20): presintered milled Co-Cr (Group M), additively manufactured Co-Cr (Group SLM), cast Co-Cr (Group C), presintered zirconia (Group Zi), and cast Ni-Cr (Group Ni).
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