AI Article Synopsis
- A novel method for creating (E)-vinyl sulfones has been introduced, utilizing a combination of iron (Fe) and copper (Cu) as co-catalysts.
- Various vinyl sulfones were successfully produced, achieving moderate to good yields similar to the best existing methods.
- This cost-effective approach offers a straightforward experimental process and shows strong compatibility with different substrates.
Article Abstract
A new approach to the selective synthesis of (E)-vinyl sulfones has been developed via a Fe/Cu co-catalyzed sulfonylation of arylpropiolic acid or phenylacetylene with sulfonyl hydrazides. A variety of vinyl sulfones have been obtained in moderate to good yields, comparable to the best results reported so far. The inexpensive Fe/Cu co-catalyzed method features a simple experimental procedure and good tolerance of substrate.
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| http://dx.doi.org/10.1021/acs.joc.5b00558 | DOI Listing |
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