Seventy-eight tuberculin-positive schoolchildren at the age of 7 to 15 years from tuberculosis foci living in special institutions of the sanatorium type were subjected to immunological examination. The control group included 22 noninfected children of the same age. Persons with lower counts of T-lymphocytes and their decreased functional activity, unbalance in their subpopulation composition and positive immunospecific responses to tuberculin predominated among the schoolchildren subjected to the examination. The state of the B-lymphocyte system changed insignificantly. It was concluded that persons with markedly suppressed cellular immunity be treated with immunomodulating agents during the chemoprophylaxis course.

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