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http://dx.doi.org/10.1097/EDE.0000000000000289 | DOI Listing |
Prehosp Emerg Care
January 2025
Graduate School of Health and Welfare, Niigata University of Health and Welfare, 1398 Shimami-cho, Kita-ku, Niigata-shi, 950-3198, Niigata, Japan,
Objectives: To compare the effects of powered and manual stretchers on participants' perceived comfort and measured acceleration during lifting and loading operations.
Methods: This non-randomized, laboratory-based crossover study involved forty-one participants (thirty-one firefighters and ten third-year paramedic students) who served as simulated patients experiencing lifting, lowering, loading, and unloading maneuvers using manual and powered stretchers. Four stretcher types were evaluated: one powered stretcher (Power-PRO™ XT) and three manual stretchers (Matsunaga GT, Exchange 4070, Scad Mate), with each group using the manual stretcher they routinely operated.
J Math Biol
January 2025
Laboratory of Mathematics and Complex Systems, Ministry of Education, School of Mathematical Sciences, Beijing Normal University, Beijing, People's Republic of China.
Networked evolutionary game theory is a well-established framework for modeling the evolution of social behavior in structured populations. Most of the existing studies in this field have focused on 2-strategy games on heterogeneous networks or n-strategy games on regular networks. In this paper, we consider n-strategy games on arbitrary networks under the pairwise comparison updating rule.
View Article and Find Full Text PDFBackground: A generative model of tau PET was applied to multiple cohorts across the Alzheimer's disease (AD) spectrum, revealing longitudinal changes in tau production and transport. A generalisation of the model accounts for amyloid, tau and neurodegeneration (ATN) interactions and accurately explains longitudinal ATN biomarker data, adding potential for region specific and individualized tracking of ATN biomarkers.
Method: A model of tau spreading and production as measured through PET was developed and applied to longitudinal data from amyloid negative (A-), amyloid positive tau negative (A+T-) and amyloid positive tau positive (A+T+) cohorts from the Alzheimer's disease neuroimaging iniative (ADNI; N = 159) and BioFINDER-2 (BF2; N = 135) datasets.
Rev Sci Instrum
January 2025
Key Laboratory of Time Reference and Applications, National Time Service Center, Chinese Academy of Sciences, Xi'an, Shaanxi 710600, China.
In this paper, two models for simulating the shot noise and electronic noise performances of resonant photodetectors designed for homodyne measurements are presented. One is based on a combination of a buffer and a low-noise amplifier, and the other is based on an operational amplifier. Through the comparisons between the numerical simulation results and the experimentally obtained data, excellent agreements are achieved, which show that the models provide a highly efficient guide for the development of a high signal-to-noise ratio (SNR) resonant photodetector.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Background: Multiple studies have linked high cortisol levels, a frequently used biomarker of stress, with the Alzheimer's disease (AD) pathophysiology. However, the relationship between cerebrospinal fluid (CSF) cortisol levels and AD-related brain atrophy is not fully understood. This study sought to investigate the cross-sectional and longitudinal association between CSF cortisol levels and brain cortical thickness in patients across the biological and clinical continuum of AD.
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