In this work, the ratchet dynamics of Brownian particles driven by an external sinusoidal (harmonic) force is investigated. The gating ratchet effect is observed when another harmonic is used to modulate the spatially symmetric potential in which the particles move. For small amplitudes of the harmonics, it is shown that the current (average velocity) of particles exhibits a sinusoidal shape as a function of a precise combination of the phases of both harmonics. By increasing the amplitudes of the harmonics beyond the small-limit regime, departures from the sinusoidal behavior are observed and current reversals can also be induced. These current reversals persist even for the overdamped dynamics of the particles.
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http://dx.doi.org/10.1103/PhysRevE.91.032920 | DOI Listing |
Bioinform Biol Insights
January 2025
Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
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March 2025
Department of Neurosurgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region 830000, P.R. China.
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January 2025
Department of Materials Science and Engineering, University of Connecticut, Storrs, Connecticut 06269, United States.
Emerging soft robots based on liquid crystal elastomers (LCEs) exhibit remarkable capabilities for large reversible shape morphing, enabling them to adapt to complex environments and perform diverse tasks such as locomotion and camouflage. Despite extensive studies, current methods for locally controlled actuation of LCE-based soft robots often involve intricate structural design, complex programming of LCEs, incorporation of multiple materials, or complex actuation methods. Here, we present a simple and efficient approach to achieve multiple deformation modes within a simply programmed LCE structure by harnessing Joule heating-induced thermal gradients across the LCE volume.
View Article and Find Full Text PDFNat Commun
January 2025
School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, 100081, China.
Designing asymmetrical structures is an effective strategy to optimize metallic catalysts for electrochemical carbon dioxide reduction reactions. Herein, we demonstrate a transient pulsed discharge method for instantaneously constructing graphene-aerogel supports asymmetric copper nanocluster catalysts. This process induces the convergence of copper atoms decomposed by copper chloride onto graphene originating from the intense current pulse and high temperature.
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January 2025
Synthetic Molecule Design and Development, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285, United States.
Single-stranded guide RNAs (sgRNAs) are important therapeutic modalities that facilitate selective genome editing by the CRISPR/Cas9 system. While these therapeutic modalities are synthesized through solid phase oligonucleotide synthesis similar to small interfering RNA (siRNAs) and antisense oligonucleotide (ASOs) therapeutics, their sequence length and complex secondary and tertiary structure hinder analytical characterization. The resulting current sgRNA methodologies have limited chromatographic selectivity near the FLP and limited MS compatibility.
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