Dynamics of the first cell cycle in parthenogenetic mouse embryos derived from ethanol-activated eggs was studied using 3H-thymidine. DNA synthesis starts within 5 h and is terminated within 10 h after activation: it lasts ca. 6 h. Changes in the intensity of 3H-thymidine incorporation and in the distribution of radioactive label between haploid and diploid parthenogens were observed. 3H-thymidine was shown to incorporate into pronucleoli of diploid parthenogens and late-labeled heterochromatin blocks were bound in both diploid and haploid pronuclei. The structure of the first cell cycle in parthenogenetic and normal embryos is discussed.

Download full-text PDF

Source

Publication Analysis

Top Keywords

parthenogenetic mouse
8
cell cycle
8
cycle parthenogenetic
8
diploid parthenogens
8
[the cycle
4
cycle dna
4
dna replication
4
replication parthenogenetic
4
mouse embryos]
4
embryos] dynamics
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!