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An integrative analysis reveals cancer risk associated with artificial sweeteners.
J Transl Med
January 2025
Medical College of YiChun University, Xuefu Road No 576, Yichun, 336000, Jiangxi, People's Republic of China.
Background: Artificial sweeteners (AS) have been widely utilized in the food, beverage, and pharmaceutical industries for decades. While numerous publications have suggested a potential link between AS and diseases, particularly cancer, controversy still surrounds this issue. This study aims to investigate the association between AS consumption and cancer risk.
View Article and Find Full Text PDFIdentification of key risk areas and failure modes using the FMEA method for the prevention and control of major infectious diseases in a stomatology department.
BMC Oral Health
January 2025
Department of Stomatology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, Zhejiang, China.
Purpose: To perform risk assessment and analysis of potential infection during stomatology workflow in a hospital in the context of a major infectious disease outbreak, and to determine the key failure modes and measures to prevent and control infection.
Method: Following the Failure Modes and Effects Analysis (FMEA) method based on the stomatology workflow, the opinions of 30 domain-experts in related fields were collected through questionnaires to determine all potential failure modes in the severity (S), occurrence (O), and detectability (D) dimensions. The group score was then integrated through the median method and the risk priority number (RPN) was obtained.
Developing clinical reasoning along the cognitive continuum: a mixed methods evaluation of a novel Clinical Diagnosis Assessment.
BMC Med Educ
January 2025
Deakin Optometry, School of Medicine, Deakin University, 75 Pigdons Road, Waurn Ponds , VIC, 3216, Australia.
Background: Clinical reasoning is a professional capability required for clinical practice. In preclinical training, clinical reasoning is often taught implicitly, and feedback is focused on discrete outcomes of decision-making. This makes it challenging to provide meaningful feedback on the often-hidden metacognitive process of reasoning to address specific clinical reasoning difficulties.
View Article and Find Full Text PDFPotentially actionable molecular alterations in particular related to poor oncologic outcomes in salivary gland carcinomas.
BMC Cancer
January 2025
Department of Tumor Biology and Genetics, Medical University of Warsaw, Warsaw, Poland.
Aim: The study was designed to evaluate molecular alterations, relevant to the prognosis and personalized therapy of salivary gland cancers (SGCs).
Materials And Methods: DNA was extracted from archival tissue of 40 patients with various SGCs subtypes. A targeted next-generation sequencing (NGS) panel was used for the identification of small-scale mutations, focal and chromosomal arm-level copy number changes.
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