Castañar cave contains the highest radon gas ((222)Rn) concentration in Spain with an annual average of 31.9 kBq m(-)(3). Seasonal variations with summer minimums and maximum values in fall were recorded. The reduction of air-filled porosity of soil and rock by condensation or rainfalls hides the radon exchange by gas diffusion, determining this seasonal stair-step pattern of the radon activity concentration in underground air. The effective total dose and the maximum hours permitted have been evaluated for the guides and public safety with a highly detailed radon measurement along 2011 and 2012. A network of 12 passive detectors (kodalphas) has been installed, as well as, two radon continuous monitoring in the most interesting geological sites of the subterranean environment. A follow up of the recommended time (max. 50 min) inside the underground environment has been analysed since the reopen to public visitors for not surpassing the legal maximum effective dose for tourists and guides. Results shown that public visitors would receive in fall a 12.1% of the total effective dose permitted per visit, whereas in summer it is reduced to 8.6%, while the cave guide received a total effective dose of 6.41 mSv in four months. The spatial radon maps allow defining the most suitable touristic paths according to the radon concentration distribution and therefore, appropriate fall and summer touristic paths are recommended.
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http://dx.doi.org/10.1016/j.jenvrad.2015.03.024 | DOI Listing |
J Radiol Prot
January 2025
Department of Biostatistics, Soon Chun Hyang University Hospital Bucheon, Bucheon, Gyeonggi-do, Korea (the Republic of).
This study investigated the additional radiation exposure, influencing factors, and clinical significance of overlapping Z-axis coverage in abdominopelvic CT scans performed consecutively after same-day chest CT scans. Data from 761 patients were analyzed, with measuring the total and overlapping Z-axis coverage of the portal venous phase in abdominopelvic CT scans. The average overlapping portion was 33.
View Article and Find Full Text PDFAnnu Rev Immunol
January 2025
3Department of Environmental Medicine and Department of Microbiology and Immunology, University of Rochester, Rochester, New York, USA; email:
Initially discovered for its role mediating the deleterious effects of environmental contaminants, the aryl hydrocarbon receptor (AHR) is now known to be a crucial regulator of the immune system. The expanding list of AHR ligands includes synthetic and naturally derived molecules spanning pollutants, phytochemicals, pharmaceuticals, and substances derived from amino acids and microorganisms. The consequences of engaging AHR vary, depending on factors such as the AHR ligand, cell type, immune challenge, developmental state, dose, and timing of exposure relative to the immune stimulus.
View Article and Find Full Text PDFN Engl J Med
January 2025
From the Department of Medicine, University of Auckland, Auckland, New Zealand (M.J.B., Z.N., A.M., C.G., V.P., B.M., A.G., I.R.R., G.G., A.H.); the Department of Psychology, Stanford University, Stanford, CA (C.G.); and the Department of Radiology, Starship Hospital, Auckland, New Zealand (S.B.).
Background: Zoledronate prevents fractures in older women when administered every 12 to 18 months, but its effects on bone density and bone turnover persist beyond 5 years. Whether infrequent zoledronate administration would prevent vertebral fractures in early postmenopausal women is unknown.
Methods: We conducted a 10-year, prospective, double-blind, randomized, placebo-controlled trial involving early postmenopausal women (50 to 60 years of age) with bone mineral density T scores lower than 0 and higher than -2.
AJR Am J Roentgenol
January 2025
Department of Radiology, Division of Breast Imaging and Intervention, Mayo Clinic, Phoenix, AZ.
Contrast-enhanced mammography (CEM) is growing in clinical use due to its increased sensitivity and specificity compared to full-field digital mammography (FFDM) and/or digital breast tomosynthesis (DBT), particularly in patients with dense breasts. To perform an intraindividual comparison of MGD between FFDM, DBT, a combination protocol using both FFDM and DBT (combined FFDM-DBT), and CEM, in patients undergoing breast cancer screening. This retrospective study included 389 women (median age, 57.
View Article and Find Full Text PDFJ Appl Oral Sci
January 2025
Universidade Federal de Uberlândia, Faculdade de Odontologia, Departamento de Periodontia e Implantodontia, Uberlândia, Brasil.
Objective: This study aimed to assess the effects of a single-dose radiation therapy (15 Gy) on grafted and non-grafted defects, bone microarchitecture, and collagen maturity.
Methodology: Bone defects were surgically created in rat femurs. The right femur defect was filled with blood clot (group "Clot") and the left femur defect by deproteinized bovine bone mineral graft (group "Xenograft").
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