AI Article Synopsis
- Cardiothoracic surgery sternal infections are challenging to manage, and there are no established guidelines for antibiotic prophylaxis.
- A study of 535 patients revealed that those treated with vancomycin experienced fewer post-surgery infections compared to those who received begalin, with males on vancomycin showing a 1.67 times higher likelihood of effective treatment than females.
- Prolonged hospitalization (over 7 days) before surgery significantly increased the risk of post-surgery infections, highlighting the potential effectiveness of vancomycin as a prophylactic option to prevent sternal wound infections.
Article Abstract
Background: Cardiothoracic surgery sternal infections are difficult to treat situations. Until now there are no clear guidelines which or if an antibiotic could be used as prophylactic treatment.
Patients And Methods: We collected retrospectively data from 535 patients from our hospital which underwent cardiothoracic surgery and recorded several biological parameters and technical aspects of the surgery.
Results: It was observed that patients to whom vancomycin was administered had less post surgery infection than those to whom begalin was administered. Male who were treated with vancomycin it was observed that they had 1.67 chances to be treated properly than female. Patients which were hospitalized for more than 7 days before surgery had 62.6% higher chances for post surgery infection.
Conclusions: It was observed that vancomycin can be used as a prophylactic treatment for cardiothoracic surgeries acting efficiently against sternal wounds.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381471 | PMC |
| http://dx.doi.org/10.3978/j.issn.2305-5839.2015.03.22 | DOI Listing |
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