AI Article Synopsis
- Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare and often underdiagnosed condition characterized by acute bilateral eye inflammation and systemic illness symptoms.
- A case study of a 15-year-old girl diagnosed with TINU syndrome highlights her acute granulomatous iridocyclitis and successful treatment with high-dose corticosteroids, which led to no relapses over a 20-month follow-up.
- The study emphasizes the importance of considering TINU syndrome in the differential diagnosis for patients experiencing acute granulomatous uveitis.
Article Abstract
Background: Tubulointerstitial nephritis and uveitis [TINU] syndrome is a rare disorder that may also be underdiagnosed. Patients with TINU syndrome typically present with an acute bilateral nongranulomatous anterior uveitis following symptoms of systemic illness.
Findings: We report the case of a 15-year-old girl who presented with acute granulomatous iridocyclitis and was diagnosed with TINU syndrome based on renal biopsy findings. Both her uveitis and interstitial nephritis promptly responded to high-dose corticosteroid treatment, and there were no relapses during follow-up of 20 months.
Conclusions: TINU should be included in the differential diagnosis of patients who present with acute granulomatous uveitis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384971 | PMC |
| http://dx.doi.org/10.1186/s12348-015-0035-2 | DOI Listing |
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