AI Article Synopsis
- Cryptococcal infections are often linked to untreated HIV/AIDS patients, but they can also occur in other immunosuppressed individuals, which is less commonly recognized.* -
- The report highlights three fatal cases of cryptococcal infections in non-HIV patients, including those with a renal transplant, corticosteroid use, and severe liver cirrhosis.* -
- In the two meningitis cases, diagnoses were delayed, and the necrotic skin infection case was identified only after death, indicating that these infections can be severe and difficult to detect early in non-HIV patients.*
Article Abstract
Cryptococcal infections are classically associated to HIV/AIDS patients without therapy, but its presence among other immunosuppressed patients is less recognized. We report 3 lethal cases in non HIV-patients. Two of them presented with meningitis associated to renal transplant or corticosteroid use and, the third, with a necrotic skin infection in the context of progressive liver cirrhosis. In the former two patients, meningeal infection was suspected late, and in the latter, the diagnosis was established postmortem. Cryptococcal infections in non-HIV immunosupressed patients can affect different sites, are suspected late and have a high case-fatality ratio.
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| http://dx.doi.org/10.4067/S0716-10182015000200015 | DOI Listing |
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