Severe acute tubular necrosis observed subsequent to oxaliplatin administration.

Clin Kidney J

Division of Nephrology, Department of Medicine , Jewish General Hospital, Montreal, QC , Canada.

Published: February 2014

AI Article Synopsis

  • A 67-year-old man with metastatic colon cancer was treated with oxaliplatin.
  • He developed severe acute kidney injury, which required dialysis for treatment.
  • A renal biopsy showed severe acute tubular necrosis, highlighting the rare but serious risk of acute kidney injury associated with oxaliplatin.

Article Abstract

A 67-year-old man known for metastatic colon cancer received treatment with oxaliplatin and developed severe acute kidney injury requiring dialysis. Renal biopsy revealed severe acute tubular necrosis. Acute kidney injury is a rare but severe adverse effect of oxaliplatin administration.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389161PMC
http://dx.doi.org/10.1093/ckj/sft148DOI Listing

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