Sixth nerve palsy + ipsilateral Horner's Syndrome = Parkinson's Syndrome.

Saudi J Ophthalmol

Neuro-ophthalmology Unit, Dept. of Ophthalmology, Buenos Aires British Hospital, Argentina.

Published: April 2015

Purpose: To present five patients with VIth nerve palsy and ipsilateral Horner's Syndrome (HS), as a result of cavernous sinus alteration.

Study Design: Consecutive case series.

Material And Methods: Five patients presented abducens palsy with horizontal diplopia (3 in primary position and 2 in lateral gaze only) and ipsilateral HS. Apraclonidine 0.5% drops evidenced sympathetic denervation in all patients 40-60 min after instillation. All 5 cases had neuroimages (MRI in 3 cases, Computerized Tomography - CT in one case and Magnetic Resonance Angiography - MRA in one case) demonstrating cavernous sinus lesions; 2 meningiomas, 1 carotid-cavernous aneurism, 1 foreign body (bullet) and 1 squamous cell carcinoma.

Conclusion: Lesions on the cavernous sinus need to be considered in cases of abducens nerve palsy and ipsilateral Horner's Syndrome.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314575PMC
http://dx.doi.org/10.1016/j.sjopt.2014.09.010DOI Listing

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