AI Article Synopsis
- * The structures of these compounds were determined using various spectroscopic techniques, including NMR, UV, and MS.
- * The new flavonoids were tested for their cytotoxic effects on four cancer cell lines, showing varying levels of potency with IC values between 13.76-22.27 μM.
Article Abstract
Three new minor prenylated flavonoids, named macadenanthins A-C (-), together with three known ones (-), were isolated from the twigs of . Their structures were elucidated on the basis of extensive spectroscopic analysis including NMR, UV and MS. The prenyl moieties in compounds - were further modified by cyclization and hydroxylation. The new compounds were tested for their cytotoxicity against four cancer cell lines (MCF-7, Hep G2, Hela and P388) and showed IC values in the range of 13.76-22.27 μM.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402582 | PMC |
| http://dx.doi.org/10.1007/s13659-015-0059-1 | DOI Listing |
Publication Analysis
Top Keywords
minor prenylated
8
prenylated flavonoids
8
flavonoids twigs
4
twigs cytotoxic
4
cytotoxic activity
4
activity three
4
three minor
4
flavonoids named
4
named macadenanthins
4
macadenanthins a-c
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!