Calcifying epithelial odontogenic tumors are rare odontogenic neoplasms that account for approximately one percent of all odontogenic tumors. Extra osseous variant is very rare with very few cases being reported in literature Peripheral Calcifying epithelial odontogenic tumor (CEOT) commonly resemble oral hyperplastic or reactive lesions and are histologically similar to their intraosseous counterparts. Here we report a rare case of gingival calcifying epithelial odontogenic tumor in the mandibular posterior region in a 31 year old female patient. Interestingly on literature review in on PubMed search only 22 case reports were available in, English literature, added to that this report will be the 23rd case.
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Arch Oral Biol
November 2024
Laboratory of Histopathology and Immunohistochemistry, School of Dentistry, Universidade Federal do Pará, Belém, Pará, Brazil. Electronic address:
Objective: The study aimed to investigate the expression of hypoxia markers associated with invadopodia in glandular odontogenic cysts and to explore an association between this expression with the aggressive biological behaviour of this odontogenic cyst.
Design: Immunohistochemistry was employed to assess the expression of hypoxia-inducible factor 1 alpha (HIF-1α), notch homologous protein of the neurogenic locus 1 (NOTCH-1), disintegrin and metalloproteinase-12 (ADAM-12), and heparin-binding epidermal growth factor (HB-EGF) in 17 samples of glandular odontogenic cysts, 10 samples of calcifying odontogenic cysts, and 10 samples of dental follicles.
Results: The glandular odontogenic cyst samples exhibited increased expression of HIF-1α, NOTCH-1, ADAM-12 and HBEGF proteins compared with calcifying odontogenic cyst and dental follicle samples.
Int J Dermatol
December 2024
Division of Dermatology, Baylor University Medical Center, Dallas, Texas, USA.
J Med Case Rep
November 2024
Department of Oral and Maxillofacial Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: Calcifying epithelial odontogenic tumor is a rare benign tumor that predominantly occurs in posterior sites of the mandible in adults.
Case Presentation: This case report describes a case of calcifying epithelial odontogenic tumor in a 37-year-old Iranian female with the chief complaint of swelling in the anterior region of the mandible and tooth displacement. This paper summarized the pathological findings, radiographical features and clinical management of the patient.
Cureus
September 2024
Department of Oral Pathology, Kothiwal Dental College and Research Centre, Moradabad, IND.
Complex odontoma is a benign odontogenic tumor composed of disorganized dental tissues, including enamel, dentin, cementum, and pulp. Unlike compound odontomas, which exhibit tooth-like structures, complex odontomas form a mass without anatomical organization. These tumors frequently present without symptoms and are typically identified inadvertently during standard dental imaging procedures.
View Article and Find Full Text PDFGalen Med J
December 2023
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Calcifying epithelial odontogenic tumor (CEOT) and ameloblastoma are types of odontogenic tumors accounting for 1%, and 10% of all the odontogenic tumors. While sharing same odontogenic origin, these tumors are found to exhibit distinct clinicopathological features. In the present study, we present the third hybrid CEOT/Ameloblastoma tumor ever reported.
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