Purpose: This was a prospective descriptive study to determine the changes in intraocular lens (IOL) position after neodymium-doped yttrium-aluminum-garnet (Nd:YAG) laser posterior capsulotomy by measuring anterior chamber depth (ACD) and refraction, including the spherical equivalent (SE) and cylinder.

Materials And Methods: Forty-seven pseudophakic eyes with posterior capsule opacification of 29 patients were included. Nd:YAG laser posterior capsulotomy was performed. Patients' ACD and refraction were measured before the treatment, as well as after the treatment at 1 week and 3 months. IOLMaster(®) and an automated refractometer were used at the Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.

Results: There were no statistically significant differences in ACD and SE before and after laser treatment at 1 week and 3 months (repeated analysis of variance, P=0.582 and P=0.269, respectively). Both backward IOL movement (number [n]=29) and forward IOL movement (n=18) were found. Some changes in cylindrical refraction were found at 1 week, but decreased at 3 months after capsulotomy (baseline cylinder: -1.16; cylinder at 1 week and 3 months: -1.00 and -1.14, respectively; P=0.012). These changes were the same with one-piece and three-piece IOLs.

Conclusion: Nd:YAG laser posterior capsulotomy did not significantly change ACD and SE. It led to cylinder change at 1 week after laser, but the effect decreased at 3 months. This effect was small and may not be clinically significant.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378868PMC
http://dx.doi.org/10.2147/OPTH.S80220DOI Listing

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