Besides the main biochemical characteristics of anti TSH-receptor antibodies, this paper points out the optimal conditions for their assays and the interpretation of results.
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| http://dx.doi.org/10.1684/abc.2014.1024 | DOI Listing |
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Association between allergic rhinitis and development of autoimmune thyroid diseases in Egyptian patients.
BMC Endocr Disord
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Internal Medicine Department, Endocrinology Unit, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Background: Autoimmune thyroid diseases (AITD) and allergic rhinitis (AR) are prevalent conditions; however, limited research has investigated their association. This study aimed to evaluate whether AR can be considered a risk factor for developing AITD.
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The predictive value of thyroid hormone sensitivity parameters for cervical lymph node metastasis in patients with differentiated thyroid cancer.
Ann Med
December 2025
Department of General Surgery, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.
Objective: To comprehensively investigate the predictive value of thyroid hormone sensitivity parameters for cervical lymph node metastasis in patients diagnosed with differentiated thyroid cancer (DTC) undergoing total thyroidectomy and neck lymph node dissection.
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Linsitinib inhibits proliferation and induces apoptosis of both IGF-1R and TSH-R expressing cells.
Front Immunol
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Molecular Thyroid Research Laboratory, Department of Medicine I, Johannes Gutenberg-University (JGU) Medical Center, Mainz, Germany.
Background: The insulin-like growth factor 1 receptor (IGF-1R) and the thyrotropin receptor (TSH-R) are expressed on orbital cells and thyrocytes. These receptors are targeted in autoimmune-induced thyroid eye disease (TED). Effective therapeutic treatment of TED inhibits activation of the IGF-1R/TSH-R complex.
View Article and Find Full Text PDFBest practices in the laboratory diagnosis, prognostication, prediction, and monitoring of Graves' disease: role of TRAbs.
BMC Endocr Disord
December 2024
Department of Endocrinology, Osmania Medical College & Osmania General Hospital, Hyderabad, Telangana, India.
Article Synopsis
- Graves' disease (GD) is an autoimmune disorder where the body's antibodies stimulate the TSH receptor, causing excessive thyroid hormone production.
- Diagnosis typically involves assessing symptoms and a thyroid panel, with specific tests for TSH Receptor Antibodies (TRAbs) aiding in diagnosis and management strategies.
- Recent guidelines from experienced endocrinologists emphasize the importance of TRAbs in GD management to improve effectiveness and decision-making for healthcare providers, particularly in South Asia.
Reference Ranges and Determinants of Thyroid Function and TSH Receptor Antibodies During Early Pregnancy in Nepal.
Clin Endocrinol (Oxf)
December 2024
Department of Internal Medicine, Academic Center for Thyroid Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands.
Objective: Different definitions of thyroid dysfunction during pregnancy may lead to under or overtreatment. The aims of this study were to (1) define population-based pregnancy-specific reference ranges for thyroid dysfunction during early pregnancy in Nepal and assess the impact of antibody positivity, (2) quantify the diagnostic impact of population-based reference ranges compared with current practice and (3) assess the determinants of thyroid function and antibody positivity.
Methods: A total of 800 healthy pregnant women aged 20-40 years in the Bhaktapur municipality were included.
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