Carbohydrates play prominent roles in immune surveillance and response to infection. Multivalency, molecular weight control, and molecular architecture control are properties that polymer science is well suited to address. Each of these properties has been demonstrated to impact the biological interaction of carbohydrate-bearing chains with their binding partners. This viewpoint highlights synthetic advances and potential applications of carbohydrate-based polymers for immune modulation. It also offers future directions in polymer science necessary for carbohydrate polymers to fulfill their potential as immune modulators.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372078 | PMC |
| http://dx.doi.org/10.1021/mz5002417 | DOI Listing |
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