Failed replications, contributing factors and careful interpretations: Commentary on Boekel et al., 2015.

Cortex

FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, UK; Wellcome Trust Centre for Neuroimaging, UCL Institute of Neurology, London, UK.

Published: January 2016

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558945PMC
http://dx.doi.org/10.1016/j.cortex.2015.02.019DOI Listing

Publication Analysis

Top Keywords

failed replications
4
replications contributing
4
contributing factors
4
factors careful
4
careful interpretations
4
interpretations commentary
4
commentary boekel
4
boekel 2015
4
failed
1
contributing
1

Similar Publications

In motor adaptation, learning is thought to rely on a combination of several processes. Two of these are implicit learning (incidental updating of the movement due to sensory prediction error) and explicit learning (intentional adjustment to reduce target error). The explicit component is thought to be fast adapting, while the implicit one is slow.

View Article and Find Full Text PDF

Atomistic adsorption of PETase onto large-scale PET 3D-models that mimic reality.

Phys Chem Chem Phys

January 2025

LAQV@REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre s/n, 4169-007, Porto, Portugal.

Polyethylene terephthalate (PET) has been widely used in plastic products, leading to massive PET waste accumulation in ecosystems worldwide. Efforts to find greener processes for dealing with post-consumer PET waste led to the discovery of PET-degrading enzymes such as PETase (PETase). studies have provided valuable contributions to this field, shedding light on the catalytic mechanisms and substrate interactions in many PET hydrolase enzymes.

View Article and Find Full Text PDF

Although urbanization is a major threat to biodiversity, some native species have managed to persist in urban areas. Populations of such species often show phenotypic differences with their rural counterparts. A crucial question is whether such differences result from different selection regimes between habitats.

View Article and Find Full Text PDF

Tyrosine phosphorylation is an important post-translational modification that regulates many biochemical signaling networks in multicellular organisms. To date, 46,000 tyrosines have been observed in human proteins, but relatively little is known about the function and regulation of most of these sites. A major challenge has been producing recombinant phospho-proteins in order to test the effects of phosphorylation.

View Article and Find Full Text PDF

Investigating the time to blood culture positivity: why does it take so long?

J Med Microbiol

January 2025

Division of Infection and Global Health, School of Medicine, University of St Andrews, St Andrews, UK.

Bloodstream infections (BSIs) are one of the most serious infections investigated by microbiologists. However, the time to detect a BSI fails to meet the rapidity required to inform clinical decisions in real time. Blood culture (BC) is considered the gold standard for diagnosing bloodstream infections.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!