Peculiarities of reparative processes of bioactive ceramic material "Syntekost", as well as reaction of structures of internal ear on these material, transplanted on osteal bulla in guinea pigs for experimental model of antromastoidotomy creation, were studied up. The signs of its resorbtion were mild, and these processes not always paralleled the osteal tissue evolvement. A newly formed osteal beams were observed up to 90-th day. In terms up to 12 mo there were preserved practically unchanged groups of granules of ceramic implanted material. New bone have evolved in a kind of foci in a distance from internal surface of osteal bulla. Inflammation or ototoxic impact of the material on structures of internal ear were not observed.
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