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Advanced Pain Management in Patients with Terminal Cancer.
Curr Med Chem
January 2025
Department of Surgery, School of Medicine, Nazarbayev University, 5/1 Kerey and Zhanibek khandar str., 020000, Astana, Kazakhstan.
Understanding and managing pain in patients with terminal cancer is a vital aspect of palliative care, aimed at relieving suffering and improving quality of life in the final stages of illness. Studies indicate that approximately 50% of patients with stage 4 cancer report moderate to severe pain, with a quarter experiencing severe cancer-related pain. Despite opioid prescriptions in 97% of cases, a significant portion of patients continues to suffer unresolved pain during the last week of life.
View Article and Find Full Text PDFEffectiveness of a Multicomponent Program for Fibromyalgia Patients in a Primary Care Setting (FIBROCARE Program): A Pragmatic Randomized Controlled Trial.
J Clin Med
December 2024
Unitat de Suport a la Recerca Terres de l'Ebre, Fundació Institut Universitari per a la Recerca al'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), 43500 Tortosa, Spain.
: Multicomponent, non-pharmacological therapies are the preferred first-line treatments for fibromyalgia (FM), but little is known about them in primary care settings. Our study assessed the effectiveness of the FIBROCARE Program in improving the quality of life, functional impact, mood, and pain of people with FM. : We conducted a pragmatic, randomized controlled trial that was not blinded for both patients and the professionals delivering the treatments in the study groups.
View Article and Find Full Text PDFTransforming dementia research into practice: a multiple case study of academic research utilization strategies in Dutch Alzheimer Centres.
Health Res Policy Syst
January 2025
Erasmus School of Health Policy & Management, PO Box 1738, 3000 DR, Rotterdam, Netherlands.
Background: Non-pharmacological dementia research products, such as social and behavioural interventions, are generated in traditional university settings. These often experience challenges to impact practices that they were developed for. The Netherlands established five specialized academic health science centres, referred to as Alzheimer Centres, to structurally coordinate and facilitate the utilization of dementia research knowledge.
View Article and Find Full Text PDFFactors associated with low health-related quality of life in persons with multiple sclerosis: A quantile-based segmentation approach.
PLoS One
November 2024
Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Article Synopsis
- Understanding the impact of Multiple Sclerosis (MS) on health-related quality of life (HRQoL) is crucial, as it tends to decline with age and longer disease duration.
- The study analyzed data from the Swiss MS Registry to explore relationships between various MS disease characteristics, symptom burdens, and low HRQoL among 1,697 individuals, identifying specific factors that contribute to diminished quality of life.
- Results indicated that low HRQoL is linked to factors such as receiving invalidity insurance, experiencing depression, muscle weakness, memory issues, pain, and severe gait impairment, highlighting the need for targeted symptom management strategies.
The WE-RISE™ multi-domain intervention: a feasibility study for the potential reversal of cognitive frailty in Malaysian older persons of lower socioeconomic status.
BMC Geriatr
October 2024
Physiotherapy Programme and Centre for Healthy Aging and Wellness, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Background: Cognitive frailty (CF) is an emerging concern among older persons, particularly within lower socioeconomic statuses (SES) populations. Currently, there is limited evidence on the potential reversibility of CF through multi-domain interventions within this demographic. This study aimed to investigate the effectiveness of the WE-RISE™ multi-domain intervention in addressing the potential reversibility of CF among community-dwelling older persons of lower SES, the intervention effects on multiple health dimensions, and to determine if WE-RISE™ is of low cost.
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