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Patterns of pharmacological treatment in patients with atrial fibrillation: an analysis from the prospective GLORIA-AF Registry Phase III.
BMC Med
January 2025
Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest Hospital, Liverpool, UK.
Background: Polypharmacy (i.e., treatment with ≥ 5 drugs) is common in patients with atrial fibrillation (AF) and has been associated with suboptimal management and worse outcomes.
View Article and Find Full Text PDFMachine learning algorithms for predicting PTSD: a systematic review and meta-analysis.
BMC Med Inform Decis Mak
January 2025
Faculty of Engineering and Information Technology, University of Technology Sydney, Ultimo, NSW, 2007, Australia.
This study aimed to compare and evaluate the prediction accuracy and risk of bias (ROB) of post-traumatic stress disorder (PTSD) predictive models. We conducted a systematic review and random-effect meta-analysis summarizing predictive model development and validation studies using machine learning in diverse samples to predict PTSD. Model performances were pooled using the area under the curve (AUC) with a 95% confidence interval (CI).
View Article and Find Full Text PDFImpact of single nucleotide polymorphisms (SNPs) in antioxidant-enzyme genes on the concentrations of folate, homocysteine and glutathione in plasma from healthy subjects after folic acid supplementation - a randomized controlled crossover trial.
Genes Nutr
January 2025
Department of Nutrition, University of Oslo (UiO), Oslo, Norway.
Background: One-carbon metabolism links folate and methionine metabolism and this is essential for nucleotide synthesis in the cells. Alterations in one-carbon metabolism are associated with cardiovascular disease (CVD), type 2 diabetes and cancer. Our aim was to investigate whether SNPs in antioxidant-enzyme genes impact the concentrations of folate in serum (s-folate), plasma total homocysteine (p-tHcy) and total glutathione in plasma (p-tGSH) in healthy subjects after supplementation with folic acid.
View Article and Find Full Text PDFSafety of laparoscopic compared to open right hepatectomy after portal vein occlusion: results from a multicenter study.
Surg Endosc
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SC Chirurgia Generale e Oncologica, Ospedale Mauriziano, Torino, Italia.
Background: Concerns have been expressed about the feasibility of laparoscopic right hepatectomy (Lap-RH) after portal vein occlusion (PVO), because of its technical difficulty. The aim of this study is to assess the safety and feasibility of lap-RH after PVO.
Methods: Retrospective analysis of prospectively collected data from high-volume HPB centers was performed.
Compromised Nipple-Areola Complex Perfusion after Reduction Mammaplasty or Mastopexy: A Retrospective Evaluation of Different Treatments.
Aesthetic Plast Surg
January 2025
Department of Plastic and Reconstructive Surgery, Marienhospital Stuttgart, Teaching Hospital of the Eberhard Karls University Tuebingen, Boeheimstraße 37, 70199, Stuttgart, Germany.
Background: Necrosis of the nipple-areolar complex (NAC) is a rare but devastating complication after reduction mammaplasty or mastopexy. Various approaches for improving compromised perfusion of the NAC have been described. However, detailed data on this topic in the literature is still scarce.
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