The urachus establishes a connection between the dome of the bladder and the umbilicus throughout fetal life. If the urachus does not close completely, malignancy is a potential complication. The primary treatment for malignant urachal tumor is surgical excision. A 61-year-old male patient diagnosed with urachal carcinoma had undergone partial cystectomy 25 years previously. Twenty years later, local recurrence was treated with another partial cystectomy without umbilical remnant excision. Recurrence at the umbilical site was excised 2 years later, but intraperitoneal invasion had occurred, and the patient underwent a total colectomy at that time. Local disease and disseminated metastases in the thorax and intra- and extraperitoneal areas were noted upon admission to our hospital. Urachal carcinomas are usually aggressive tumors, and surgical treatment should include partial or radical cystectomy and excision of the urachus and umbilicus, to prevent local recurrence and distant metastasis.
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http://dx.doi.org/10.1155/2015/183787 | DOI Listing |
Int J Surg Case Rep
December 2024
Faculty of Medicine, Polytechnic University of Palestine, Hebron, Palestine; Department of Urology, Governmental Hebron Hospital, Palestine.
Introduction And Importance: Urachal carcinoma (UrC) is a rare bladder malignancy originating from the urachus. Comprising around 90 % adenocarcinomas, most cases are invasive. Urachal adenocarcinoma is less common than its non-urachal counterpart and is recognized for its aggressive nature, often diagnosed at advanced stages with a poor prognosis.
View Article and Find Full Text PDFThorac Cancer
December 2024
Department of Thoracic Surgery, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Cancer Med
October 2024
Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.
Background And Aim: Pseudomyxoma peritonei (PMP) is an unusual condition with unique behaviour caused by a mucinous neoplasm, usually arising from the appendix. The aim of this study was to evaluate the prevalence of genomic alterations in clinical specimens of PMP using a targeted assay and correlate the findings with clinical, pathological and outcome data. Sequencing data from 223 patients were analysed.
View Article and Find Full Text PDFFront Oncol
September 2024
Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
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