During the interaction of a laser pulse with the surface of a solid object, the object always gains momentum. The delivered force impulse is manifested as propulsion. Initially, the motion of the object is composed of elastic waves that carry and redistribute the acquired momentum as they propagate and reflect within the solid. Even though only ablation- and light-pressure-induced mechanical waves are involved in propulsion, they are always accompanied by the ubiquitous thermoelastic waves. This paper describes 1D elastodynamics of pulsed optical manipulation and presents two diametrical experimental observations of elastic waves generated in the confined ablation and in the radiation pressure regime.
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http://dx.doi.org/10.1364/OE.23.007978 | DOI Listing |
ACS Appl Mater Interfaces
January 2025
Faculty of Life Sciences, Department of Pharmaceutical Sciences, Laboratory of Macromolecular Cancer Therapeutics (MMCT), University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria.
Splice-switching oligonucleotides (SSOs) can restore protein functionality in pathologies and are promising tools for manipulating the RNA-splicing machinery. Delivery vectors can considerably improve SSO functionality in vivo and allow dose reduction, thereby addressing the challenges of RNA-targeted therapeutics. Here, we report a biocompatible SSO nanocarrier, based on redox-responsive disulfide cross-linked low-molecular-weight linear polyethylenimine (cLPEI), for overcoming multiple biological barriers from subcellular compartments to en-route serum stability and finally in vivo delivery challenges.
View Article and Find Full Text PDFNano Lett
January 2025
Department of Electrical & Systems Engineering, Washington University in St. Louis, St. Louis, Missouri 63130, United States.
Dielectric metasurfaces have emerged as an unprecedented platform for precise wavefront manipulation at subwavelength scales with nearly zero loss. When aiming at dynamic applications such as AR/VR and LiDAR, high-quality factor (high-Q) phase gradient metasurfaces have emerged as a way to boost weak light-material interactions in flat-optical components. However, resonant features are naturally tied to polarization, limiting devices to operating on a single polarization state, which reduces the efficiency and adaptability of wave-shaping.
View Article and Find Full Text PDFInnovation (Camb)
January 2025
Center for Intelligent Biomedical Materials and Devices (IBMD), Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen 518055, China.
Optical tweezers and related techniques offer extraordinary opportunities for research and applications in physical, biological, and medical fields. However, certain critical requirements, such as high-intensity laser beams, sophisticated electrode designs, additional electric sources, or low-conductive media, significantly impede their flexibility and adaptability, thus hindering their practical applications. Here, we report innovative photopyroelectric tweezers (PPT) that combine the advantages of light and electric field by utilizing a rationally designed photopyroelectric substrate with efficient and durable photo-induced surface charge-generation capability, enabling diverse manipulation in various working scenarios.
View Article and Find Full Text PDFSci Rep
January 2025
College of Physics and Electronic Science, Hubei Normal University, Huangshi, 435002, P. R. China.
We propose a double-cavity optomechanical system with nonreciprocal coupling to realize tunable optical nonreciprocity that has the prospect of making an optical device for the manipulation of information processing and communication. Here we investigate the steady-state dynamic processes of the double-cavity system and the transmission of optical waves from opposite cavity directions. The transmission spectrum of the probe field is presented in detail and the physical mechanism of the induced transparency window is analyzed.
View Article and Find Full Text PDFNat Commun
January 2025
Institute for Advanced Biosciences, Team: Epigenetics, Immunity, Metabolism, Cell Signaling & Cancer, Inserm U 1209, CNRS UMR 5309, Univ. Grenoble Alpes, Grenoble, France.
Dendritic cells (DC) are key players in antitumor immune responses. Tumors exploit their plasticity to escape immune control; their aberrant surface carbohydrate patterns (e.g.
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