We propose and demonstrate optofluidic tunable manipulation of polystyrene microparticles based on the combination of a graded-index fiber (GIF) taper and a microcavity. The tunability on the manipulation length is experimentally explored by changing the balance between the optical force and the microfluidic flow force, as well as by tuning the focus of light emitting from the GIF taper via adjusting the length of an air microcavity. By optimizing the geometric shape of the GIF taper, as well as the flow rate and laser power, a manipulation length of 177 μm is achieved, more than 4 times longer than the state-of-the-art optical fiber tweezers. This method has advantages of high flexibility, ease of fabrication and use, integration with microfluidics and has the potential for optofluidic sensing applications.
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http://dx.doi.org/10.1364/OE.23.003762 | DOI Listing |
The fulfilment of the adiabatic criterion is indispensable for the realization of a low-loss photonic lantern (PL), concurrently imposing a stringent restriction on the taper transition length of the PL. Here, by relaxing the adiabatic criterion, a low-loss and compact PL based on a step-index double cladding fiber (SI-DCF) is theoretically proposed and experimentally demonstrated. The use of SI-DCF can reduce the mode field diameter (MFD) expansion ratio during the tapering processing and greatly decrease the taper transition length required for adiabatic tapering.
View Article and Find Full Text PDFBrain
February 2024
Service de Neurologie, NS-Park/F-CRIN network, Hôpitaux Universitaires de Strasbourg et Fédération de Médecine Translationnelle de Médecine de Strasbourg, 67200 Strasbourg, France.
Postoperative apathy is a frequent symptom in Parkinson's disease patients who have undergone bilateral deep brain stimulation of the subthalamic nucleus. Two main hypotheses for postoperative apathy have been suggested: (i) dopaminergic withdrawal syndrome relative to postoperative dopaminergic drug tapering; and (ii) direct effect of chronic stimulation of the subthalamic nucleus. The primary objective of our study was to describe preoperative and 1-year postoperative apathy in Parkinson's disease patients who underwent chronic bilateral deep brain stimulation of the subthalamic nucleus.
View Article and Find Full Text PDFInvest Radiol
August 2022
From the Guerbet Research, Villepinte.
Objectives: The aim of this study was to evaluate a deep learning method designed to increase the contrast-to-noise ratio in contrast-enhanced gradient echo T1-weighted brain magnetic resonance imaging (MRI) acquisitions. The processed images are quantitatively evaluated in terms of lesion detection performance.
Materials And Methods: A total of 250 multiparametric brain MRIs, acquired between November 2019 and March 2021 at Gustave Roussy Cancer Campus (Villejuif, France), were considered for inclusion in this retrospective monocentric study.
We propose and demonstrate optofluidic tunable manipulation of polystyrene microparticles based on the combination of a graded-index fiber (GIF) taper and a microcavity. The tunability on the manipulation length is experimentally explored by changing the balance between the optical force and the microfluidic flow force, as well as by tuning the focus of light emitting from the GIF taper via adjusting the length of an air microcavity. By optimizing the geometric shape of the GIF taper, as well as the flow rate and laser power, a manipulation length of 177 μm is achieved, more than 4 times longer than the state-of-the-art optical fiber tweezers.
View Article and Find Full Text PDFLong manipulation length is critical for optical fiber tweezers to enhance the flexibility of non-contact trapping. In this paper a long manipulation distance of more than 40 μm is demonstrated experimentally by the graded-index fiber (GIF) tweezers, which is fabricated by chemically etching a GIF taper with a large cone angle of 58°. The long manipulation distance is obtained by introducing an air cavity between the lead-in single mode fiber and the GIF as well as by adjusting the laser power in the existence of a constant background flow.
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