In children with acute leukemia, at the initial period of the disease the absolute number of T-lymphocytes is within the normal range, when the values of the total number of leucocytes is low or normal, and it is increased in cases with high initial leucocytosis. Dissociation of T-cell marker signs in the lymphocyte population has been revealed that evidences the presence of functionally defective T-cells in the circulation. The value of the relative content of E+ T-cells over 10% in the circulation is of prognostic significance.
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