Postural orthostatic tachycardia syndrome (POTS) is a type of dysautonomia seen most commonly in young women and children. It is defined as an increase in heart rate of 30 beats per minute (bpm) or more within 10 minutes of standing in adults, or by 40 bpm or more in children in the absence of orthostatic hypotension. In addition to typical autonomic symptoms, POTS patients report a wide range of subjective complaints in multiple organ systems, though the exact frequencies are unclear. To address the symptom frequency, we had 39 patients with POTS at our institution complete an intake form consisting of a list of 37 symptoms. The most frequently reported symptoms included palpitations, lightheadedness, and headache, although sleep disturbances, gastrointestinal complaints, sensitivity to temperature, and rash were also common.
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http://dx.doi.org/10.1080/08998280.2015.11929217 | DOI Listing |
BMC Geriatr
December 2024
Faculty of Science, Palacký University Olomouc, Olomouc, Czech Republic.
Introduction: Obesity in older adults is linked to various chronic conditions and decreased quality of life. Traditional physical activity guidelines often overlook the specific postures and movements that older adults engage in daily. This study aims to explore the compositional associations between posture-specific behaviours and obesity risk in younger (M = 67.
View Article and Find Full Text PDFArch Orthop Trauma Surg
December 2024
Sitaram Bhartia Institute of Science and Research, New Delhi, India.
Purpose: Achieving precise postoperative alignment is critical for the long-term success of total knee arthroplasty (TKA). Long-leg standing radiograph (LLR) at 6 weeks post-op is the gold standard for assessing alignment, but its reliance on weight-bearing and positioning makes it less practical in the early postoperative period. Supine computed tomography scanogram (CTS) offers a potential alternative.
View Article and Find Full Text PDFSci Rep
December 2024
Multi-Modality Medical Imaging (M3I), TechMed Centre, University of Twente, Technohal 2384,Drienerolaan 5, Enschede, 7522NB, The Netherlands.
Vaginal pessaries have been used for millennia to alleviate symptoms of pelvic organ prolapse (POP). Despite their long-standing use, the success rate of pessary treatment is approximately 60%, and the underlying mechanisms of support are not well understood. This study aims to investigate three previously proposed hypotheses regarding the support mechanisms of pessaries, utilizing supine and upright magnetic resonance imaging (MRI): (1) support by bony structures, (2) support by levator ani muscles (LAM), and (3) the uterus keeping the pessary in place by acting as a lever.
View Article and Find Full Text PDFHypertension
December 2024
Vanderbilt Autonomic Dysfunction Center, Division of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN. (L.E.O., A.D., C.A.S., A.G., B.K.B., S.P., I.B.).
Background: The cholinesterase inhibitor pyridostigmine is used to treat orthostatic hypotension by facilitating cholinergic neurotransmission in autonomic ganglia, thereby harnessing residual sympathetic tone to increase blood pressure (BP) preferentially in the upright posture. We hypothesized that less severe autonomic impairment was associated with greater pressor responses to pyridostigmine.
Methods: To identify predictors of pressor response, linear regression analyses between the effect of pyridostigmine on upright BP and markers of autonomic impairment were retrospectively conducted on 38 patients who had a medication trial with pyridostigmine (60 mg single dose).
Hum Mov Sci
December 2024
Univ. Lille, CNRS, UMR 9193 - SCALab, Sciences Cognitives et Sciences Affectives, F-59000 Lille, France. Electronic address:
Background And Aim: Sit-stand desks allow individuals to work in either sitting or standing position. While previous studies have reported better performance on the attention network test (ANT) while standing compared to sitting, the relationship between body sway induced by these positions and ANT performance remains unclear. In this study, we aimed to test and expect benefits of body sway (in terms of magnitude and complexity) and improvements in ANT performance when standing (e.
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